ChemicalBook > CAS DataBase List > ELA-11 (human)
ELA-11 (human)
- Product Name
- ELA-11 (human)
- CAS No.
- 1784687-32-6
- Chemical Name
- ELA-11 (human)
- Synonyms
- ELA-11 (human);L-Proline, L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-
- CBNumber
- CB44902715
- Molecular Formula
- C58H90N16O13S2
- Formula Weight
- 1283.56
- MOL File
- 1784687-32-6.mol
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ELA-11 (human) Property
- Density
- 1.47±0.1 g/cm3(Predicted)
- form
- Solid
- pka
- 3.43±0.20(Predicted)
- color
- White to off-white
- Sequence
- Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro
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ELA-11 (human) Chemical Properties,Usage,Production
Uses
ELA-11(human), a peptide, is a full agonist of human apelin receptor, with a pKi of 7.85. ELA-11(human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment[1].
References
[1] Yang P, et, al. Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension. Circulation. 2017 Mar 21;135(12):1160-1173. DOI:10.1161/CIRCULATIONAHA.116.023218
ELA-11 (human) Preparation Products And Raw materials
Raw materials
Preparation Products
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ELA-11 (human) Suppliers
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9923
- Advantage
- 65