BAY-598 R-isomer

Product Name: BAY-598 R-isomer
CAS No.: 1906920-28-2
Chemical Name: BAY-598 R-isomer
Synonyms: (R)-BAY-598;BAY-598 R-isomer;BAY598 Risomer,BAY 598 R isomer;N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-acetamide;Acetamide, N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-
CBNumber: CB44920777
Molecular Formula: C22H20Cl2F2N6O3
Formula Weight: 525.34
MOL File: 1906920-28-2.mol

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BAY-598 R-isomer Property

Boiling point:: 663.5±65.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A solid
pka: 13.34±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29174
Product name: (R)-BAY-598
Packaging: 1mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 29174
Product name: (R)-BAY-598
Packaging: 10mg
Price: $494
Updated: 2024/03/01

Cayman Chemical

Product number: 29174
Product name: (R)-BAY-598
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 29174
Product name: (R)-BAY-598
Packaging: 5mg
Price: $266
Updated: 2024/03/01

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BAY-598 R-isomer Chemical Properties,Usage,Production

Description

BAY-598 R-isomer is the R-isomer of BAY589. BAY-598 R-isomer may be used as a reference compound. BAY-598 is a potent, peptide-competitive chemical probe for SMYD2. BAY-598 has a unique chemotype relative to the current SMYD2 chemical probe LLY-507. BAY-598 inhibits in vitro methylation of p53K370 with IC50 = 27 nM and has more than 100-fold selectivity over other histone methyltransferases and other non-epigenetic targets. BAY-598 inhibits the methylation of p53K370 in cells with IC50 < 1 μM. (Further to this, BAY-598 has properties that are compatible with in vivo experiments.) A control compound, BAY-369, has also been developed. BAY-369 inhibits the in vitro methylation of p53K370 with IC50 > 70 micromolar.

BAY-598 R-isomer Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-598 R-isomer Suppliers

China 8 United States 3 USA 1 Global 12

Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

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Changzhou Furuisi Biotechnology Co., Ltd

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InvivoChem

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TargetMol Chemicals Inc.

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Nanjing Tengyi Biotechnology Co., Ltd

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Shanghai Yifei Biotechnology Co. , Ltd.

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1906920-28-2, BAY-598 R-isomerRelated Search:

BAY-598 R-isomer

(R)-BAY-598

BAY598 Risomer,BAY 598 R isomer

Acetamide, N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-

N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-acetamide

1906920-28-2