MERBARONE

Product Name: MERBARONE
CAS No.: 97534-21-9
Chemical Name: MERBARONE
Synonyms: RLBN1001;RLBN-1001;MERBARONE;NSC-336628;Merbarone - CAS 97534-21-9 - Calbiochem;5-(N-PHENYLCARBAMOYL)-2-THIOBARBITURIC ACID;5-(N-PHENYLCARBOXAMIDO)-2-THIOBARBITURIC ACID;5-(N-Phenylcarbamoyl)-2-thiobarbituric acid, NSC-336628;hexahydro-4,6-dioxo-n-phenyl-2-thioxo-5-pyrimidinecarboxamid;4,6-Dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide
CBNumber: CB4494665
Molecular Formula: C11H9N3O3S
Formula Weight: 263.27
MOL File: 97534-21-9.mol

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MERBARONE Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >5mg/mL
form: solid
pka: -2.16±0.20(Predicted)
color: Pink to purple

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Safety

WGK Germany: 3
RTECS: UV7714625

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M2070
Product name: Merbarone
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $161
Updated: 2024/03/01

Sigma-Aldrich

Product number: 445800
Product name: Merbarone
Packaging: 25mg
Price: $144
Updated: 2024/03/01

TRC

Product number: M800603
Product name: Merbarone
Packaging: 25mg
Price: $100
Updated: 2021/12/16

Usbiological

Product number: 454363
Product name: Merbarone
Packaging: 25mg
Price: $375
Updated: 2021/12/16

ChemScene

Product number: CS-0014735
Product name: Merbarone
Purity: ≥99.0%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

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MERBARONE Chemical Properties,Usage,Production

Uses

Merbarone has been used to study its effect on the occurrence of DNA lesions.

General Description

A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes (IC₅₀ = 20 μM for purified mammalian topo II versus IC₅₀ = ~ 200 μM for topo I). Also induces apoptosis in human leukemic CEM cells through a caspase-3-like protease-dependent mechanism.

Biochem/physiol Actions

Cell permeable: yes

MERBARONE Preparation Products And Raw materials

Raw materials

Preparation Products

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MERBARONE Suppliers

China 27 Switzerland 1 United Kingdom 4 United States 9 Global 41

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Jinan Sanyuan Chemical Co. LTD

Tel: 0531-58582194 13335164090
Fax: 0531-58585914
Email: 1660423085@qq.com
Country: China
ProdList: 405
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10002
Advantage: 58

Shanghai Naiys Biological Technology Co., Ltd

Tel: 18321139117
Email: 316441092@qq.con
Country: China
ProdList: 3011
Advantage: 58

Zhengzhou convergence chemical co., LTD

Tel: 0371-0371-55153829 18003835034
Fax: 18003835034（微信）
Email: 2853979819@qq.com
Country: China
ProdList: 9718
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62163
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18478
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24647
Advantage: 58

97534-21-9, MERBARONERelated Search:

MERBARONE

4,6-dioxo-N-phenyl-2-sulfanylidene-1,3-diazinane-5-carboxamide

Merbarone - CAS 97534-21-9 - Calbiochem

5-(N-PHENYLCARBAMOYL)-2-THIOBARBITURIC ACID

5-(N-PHENYLCARBOXAMIDO)-2-THIOBARBITURIC ACID

NSC-336628

hexahydro-4,6-dioxo-n-phenyl-2-thioxo-5-pyrimidinecarboxamid

5-(N-Phenylcarbamoyl)-2-thiobarbituric acid, NSC-336628

MERBARONE

5-Pyrimidinecarboxamide, hexahydro-4,6-dioxo-N-phenyl-2-thioxo-

RLBN1001

RLBN-1001

4,6-Dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide , Merbarone

4,6-Dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide

97534-21-9

Reagents

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