1-DODECYLIMIDAZOLE

Product Name: 1-DODECYLIMIDAZOLE
CAS No.: 4303-67-7
Chemical Name: 1-DODECYLIMIDAZOLE
Synonyms: C12IM;SKL1556;SKL1462;1-dodecliMidazole;1-laurylimidazole;n-laurylimidazole;N-DODECYLIMIDAZOLE;1-DODECYLIMIDAZOLE;1-dodecyl-imidazol;1-dodecyl-1h-imidazol
CBNumber: CB4495420
Molecular Formula: C15H28N2
Formula Weight: 236.4
MOL File: 4303-67-7.mol

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1-DODECYLIMIDAZOLE Property

Melting point:: 69.5-70.5 °C(Solv: ethyl acetate (141-78-6))
Boiling point:: 146 °C (0.5 mmHg)
Density: 0.9624 (rough estimate)
vapor pressure: 0.009Pa at 20℃
refractive index: 1.5312 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Liquid
pka: 7.08±0.10(Predicted)
color: Clear yellow
InChI: InChI=1S/C15H28N2/c1-2-3-4-5-6-7-8-9-10-11-13-17-14-12-16-15-17/h12,14-15H,2-11,13H2,1H3
InChIKey: JMTFLSQHQSFNTE-UHFFFAOYSA-N
SMILES: C1N(CCCCCCCCCCCC)C=CN=1
LogP: 3.56-5.5 at pH5-9
Surface tension: 45mN/m at 20mg/L and 20℃
EPA Substance Registry System: 1H-Imidazole, 1-dodecyl- (4303-67-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26
HS Code: 29332990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D6012
Product name: 1-Dodecyl-1H-imidazole
Purity: min. 97.0 %
Packaging: 1G
Price: $53
Updated: 2025/07/31

TCI Chemical

Product number: D6012
Product name: 1-Dodecyl-1H-imidazole
Purity: min. 97.0 %
Packaging: 5G
Price: $159
Updated: 2025/07/31

TRC

Product number: D494700
Product name: N-Dodecylimidazole
Packaging: 5g
Price: $350
Updated: 2021/12/16

Matrix Scientific

Product number: 128510
Product name: 1-Dodecyl-1H-imidazole
Purity: 97%
Packaging: 1g
Price: $179
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22591
Product name: N-Dodecylimidazole
Packaging: 1g
Price: $180
Updated: 2021/12/16

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1-DODECYLIMIDAZOLE Chemical Properties,Usage,Production

Chemical Properties

Clourless Liquid

Uses

A N-alkylated derivative of imidazole as antibacterial agent.

Synthesis

288-32-4

143-15-7

4303-67-7

Imidazole (0.68 g, 10 mmol) and bromododecane (2.5 g, 10 mmol) were added to anhydrous potassium carbonate (2.76 g, 20 mmol) in a 50 mL round-bottomed flask and dissolved in 20 mL of acetone. The mixed solution was heated to reflux for 7 hours. After completion of the reaction, the acetone solvent was removed by rotary evaporation. The crude product was purified by column chromatography using ethyl acetate as eluent. After collecting the target components, the ethyl acetate solvent was removed by rotary evaporation under reduced pressure and the final product was dried under vacuum to give purified 1-dodecylimidazole in 90% yield.

in vivo

The hypocholesterolaemic activity of 1-dodecylimidazole results in part from the inhibition of cholesterol biosynthesis at the level of 2,3-oxidosqualene sterol cyclase^[2].
1-dodecylimidazole (150 mg/kg body wt; by stomach tube; daily for 10 days) has lower serum cholesterol concentrations than control rats^[2].

Animal Model:	Male rats^[2]
Dosage:	150 mg/kg body wt
Administration:	By stomach tube; daily for 10 days
Result:	Had significantly lower serum cholesterol concentrations than untreated animals.

References

[1] Russian Journal of Organic Chemistry, 2013, vol. 49, # 9, p. 1291 - 1299
[2] Zh. Org. Khim., 2013, vol. 49, # 9, p. 1308 - 1316,9
[3] Patent: CN106188014, 2016, A. Location in patent: Paragraph 0016
[4] Patent: CN103951702, 2016, B. Location in patent: Paragraph 0059; 0060
[5] Tetrahedron, 2010, vol. 66, # 35, p. 7077 - 7082

1-DODECYLIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-DODECYLIMIDAZOLE Suppliers

Belgium 1 Canada 1 China 78 Germany 1 India 4 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 8 United States 11 Global 108

Zhengzhou Ruijia Pharmaceutical Technology Co. LTD

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View Lastest Price from 1-DODECYLIMIDAZOLE manufacturers

henan kanbei chemical co.,ltd

Product: 1-DODECYLIMIDAZOLE 4303-67-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2022-09-19

Career Henan Chemical Co

Product: 1-DODECYLIMIDAZOLE 4303-67-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-19

4303-67-7, 1-DODECYLIMIDAZOLERelated Search:

1-TETRADECYL-3-METHYLIMIDAZOLIUM CHLORIDE 1-DODECYL-2-METHYL-3-BENZYLIMIDAZOLIUM CHLORIDE 1-DODECYLIMIDAZOLE 1-HEXADECYL-3-METHYLIMIDAZOLIUM CHLORIDE MONOHYDRATE 3-METHYL-1-OCTADECYLIMIDAZOLIUM CHLORIDE 1-DODECYL-3-METHYLIMIDAZOLIUM CHLORIDE 1-HEXADECYL-3-METHYLIMIDAZOLIUM CHLORIDE 1-DODECYL-3-METHYLIMIDAZOLIUM BROMIDE 3-METHYL-1-OCTADECYLIMIDAZOLIUM BIS(TRIFLUOROMETHYLSULFONYL)IMIDE 1-Dodecyl-3-methylimidazolium iodide 1-HEXADECYL-2,3-DIMETHYLIMIDAZOLIUM CHLORIDE 1-Methyl-2-phenyl-3-dodecylbenzimidazolinium ferrocyanide NH125 3-METHYL-1-OCTADECYLIMIDAZOLIUM HEXAFLUOROPHOSPHATE 1-N-DODECYL-2-PHENYLBENZIMIDAZOLE (1-octadecyl-1H-benzimidazol-2-yl)methanol SALOR-INT L248770-1EA SALOR-INT L249106-1EA

1-DODECYLIMIDAZOLE

1-DODECYL-1H-IMIDAZOLE

1-dodecyl-1h-imidazol

1-dodecyl-imidazol

1-laurylimidazole

1-Dodecylimidazole,95%

n-laurylimidazole

N-DODECYLIMIDAZOLE

1-Dodecylimidazole,97%

1-dodecliMidazole

1-DodecyliMidazole, GC 97%

C12IM

1H-Imidazole, 1-dodecyl-

SKL1556

SKL1462

conditions,1-Dodecylimidazole,Inhibitor,Fungal,N-Dodecylimidazole,acidic,extracellular,1 Dodecylimidazole,tumors,properties,inhibit,1Dodecylimidazole,detergent

Imidazole, 1-dodecyl-

1-Dodecylimidazole, 10 mM in DMSO

4303-67-7

C15H28N2

Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines

Imidazoles & Benzimidazoles

Miscellaneous Reagents

Imidazoles & Benzimidazoles

Heterocycles