(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE

ChemicalBook > CAS DataBase List > (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE

(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE

Reaction

Product Name: (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE
CAS No.: 277306-29-3
Chemical Name: (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE
Synonyms: Dichloro[1,1'-Bis(diphenylphosphino)ferrocene]palladium;(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine;(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE;(S)-(-)-1-[(Rp)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine;(S)-(-)-1-[(Rp)-3-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine;(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine >=97%;(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine,min.97%;(S)-(+)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-T-BUTYLPHOSPHINE, MIN. 97%;(s,s)-1-[1-(di-tert-butylphosphino)ethyl]-2-(diphenylphosphino]ferrocene (acc to cas);(2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene
CBNumber: CB4497505
Molecular Formula: C32H40FeP2
Formula Weight: 542.45
MOL File: 277306-29-3.mol

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(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE Property

alpha: +412° ±15° (c 0.5, CHCl3)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Powder
color: orange
optical activity: [α]20/D +410±15°, c = 0.5 in chloroform

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 88720
Product name: (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
Purity: ≥97%
Packaging: 100mg
Price: $103
Updated: 2024/03/01

Sigma-Aldrich

Product number: 88720
Product name: (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
Purity: ≥97%
Packaging: 1g
Price: $204.8
Updated: 2024/03/01

Strem Chemicals

Product number: 26-1201
Product name: (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine, min. 97%
Packaging: 100mg
Price: $107
Updated: 2024/03/01

Strem Chemicals

Product number: 26-1201
Product name: (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine, min. 97%
Packaging: 500mg
Price: $375
Updated: 2024/03/01

Sigma-Aldrich

Product number: 88720
Product name: (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
Purity: ≥97%
Packaging: 500mg
Price: $359
Updated: 2024/03/01

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(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE Chemical Properties,Usage,Production

Reaction

Ferrocenylphosphine ligands of the type cpFecp(PR2)(*CH(CH3)PR'2) are a class of asymmetric ligands developed at Solvias in Basel, Switzerland . Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products. A unique feature of these bidentate ligands is the presence of a fixed phosphine moiety and a stereogenic, functionalized side chain, which can be easily modified to accommodate electronic and steric requirements. Based on a versatile synthetic procedure starting with optically active ferrocenes of the type cpFecp(PR2)(*CH(CH3)X) [X = OAc or NR2], a variety of donor atoms can be introduced into the side chain. These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, β-ketoesters and simple alkenes.
Useful as a ligand in Pd-catalyzed C-N bond-forming reactions.
Pd-catalyzed enantioselective alkylative desymmetrization of meso-succinic anhydrides.
Asymmetric hydrogenation of ketones and phosphinylketimines.
Michael addition of Grignard reagents to ",$-unsaturated esters and thioesters.
Boration of ",$-unsaturated esters and nitriles.
Reaction of aryl halides with ammonia.
Cu-catalyzed reduction of activated C=C bonds with PMHS.
Regio- and enantioselective hydroboration of vinyl arenes.
Rh-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes.
1,2-Migrations in Pd-catalyzed Negishi couplings with JosiPhos ligands.

Chemical Properties

Orange powder

Uses

(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine is β-boration catalyst; used in preparation of Sitagliptin β-Amino-2,4,5-trifluorobenzenebutanoic Acid derivatives intermediates via Grignard exchange reaction, cross coupling, β-boration, oxidation and Amination.

General Description

sold in collaboration with Solvias AG

(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE manufacturers

XINXIANG RUNYU MATERIAL CO., LTD.

Product: S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine 277306-29-3
Price: US $0.00-0.00/g
Min. Order: 1KG
Purity: 0.99
Supply Ability: 500kg
Release date: 2021-12-01

Career Henan Chemical Co

Product: di(naphthalen-1-yl)phosphine oxide 277306-29-3
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 1MT
Release date: 2018-08-10

277306-29-3, (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINERelated Search:

(S,S)-1-DICYCLOHEXYLPHOSPHINO-2-[1-(DICYCLOHEXYLPHOSPHINO)ETHYL]FERROCENE (S)-(R)-JOSIPHOS T-BUTYLPHOSPHINE (S)-1-[(R)-2-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE (S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE TRIISOPROPYLPHOSPHINE TERT-BUTYLDIISOPROPYLPHOSPHINE DI-T-BUTYL(I-PROPYL)PHOSPHINE 1,3-BIS(DIMETHYLPHOSPHINO)PROPANE (S)-1-[(R)-2-[DI(1-NAPHTHYL)PHOSPHINO]FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE Di-tert-butylphosphine

1,2,3,4,5-Cyclopentanepentayl, compd. with 1-[(1S)-1-[bis(1,1-dim ethylethyl)phosphino]ethyl]-2-(diphenylphosphino)-1,2,3,4,5-cyclo pentanepentayl, iron salt (1:1:1)

(2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene

(S)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]-ETHYLDI-TERT.-BUTYLPHOSPHINE

(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine,min.97%

(s,s)-1-[1-(di-tert-butylphosphino)ethyl]-2-(diphenylphosphino]ferrocene (acc to cas)

(S)-(+)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-T-BUTYLPHOSPHINE, MIN. 97%

(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine

Josiphos SL-J002-2, (2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS)

(2R)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene

(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine >=97%

(S)-(-)-1-[(Rp)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine

Ferrocene, 1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)-, (2S)-

Ferrocene,1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)-, (2S)-(9CI)

(S)-(-)-1-[(Rp)-3-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine

(2Rp)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene

cyclopenta-2,4-dien-1-yl-[(1S)-3-[(1S)-1-ditert-butylphosphanylethyl]-4-diphenylphosphanyl-cyclopenta-2,4-dien-1-yl]iron

(2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene (ACI)

Dichloro[1,1'-Bis(diphenylphosphino)ferrocene]palladium

277306-29-3

C27H35P2C5H5Fe

Ferrocene Series

Josiphos Series

Chiral Phosphine

organophosphine ligand