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(S)-(R)-JOSIPHOS

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Product Name
(S)-(R)-JOSIPHOS
CAS No.
162291-02-3
Chemical Name
(S)-(R)-JOSIPHOS
Synonyms
Josiphos SL-J001-2 / (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine;(S)-(R)-JOSIPHOS;JOSIPHOS SL-J001-2;97% (S)-(R)-JOSIPHOS;dichloromethane complex;(S)1 (1R)2(DIPHENYLPHOSPHINO)FERROCENYL&;(S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl];(S)1[(1R)2(diphenylphosphino)ferrocenyl] et-dicyclohexylphos;(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenylethyl]dicycloh...;(S)-1-[(1R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
CBNumber
CB8268578
Molecular Formula
C36H44FeP210*
Formula Weight
594.53
MOL File
162291-02-3.mol
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(S)-(R)-JOSIPHOS Property

alpha 
+360° (c 0.5, CHCl3)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Powder
color 
orange
Stability:
store cold
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
10
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
88718
Product name
(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
Purity
≥97%
Packaging
1g
Price
$662
Updated
2024/03/01
Sigma-Aldrich
Product number
88718
Product name
(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
Purity
≥97%
Packaging
5g
Price
$2250
Updated
2023/01/07
Strem Chemicals
Product number
26-1211
Product name
(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct, min. 97% (S)-(R)-JOSIPHOS
Packaging
100mg
Price
$107
Updated
2024/03/01
Strem Chemicals
Product number
26-1211
Product name
(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct, min. 97% (S)-(R)-JOSIPHOS
Packaging
500mg
Price
$375
Updated
2024/03/01
Sigma-Aldrich
Product number
88718
Product name
(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
Purity
≥97%
Packaging
100mg
Price
$87.6
Updated
2024/03/01
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(S)-(R)-JOSIPHOS Chemical Properties,Usage,Production

Reactions

  1. Ferrocenylphosphine ligands of the type cpFecp(PR2)(*CH(CH3)PR'2) are a class of asymmetric ligands developed at Solvias in Basel, Switzerland. Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products. A unique feature of these bidentate ligands is the presence of a fixed phosphine moiety and a stereogenic,functionalized side chain, which can be easily modified to accommodate electronic and steric requirements. Based on a versatile synthetic procedure starting with optically active ferrocenes of the type cpFecp(PR2)(*CH(CH3)X) [X = OAc or NR2], a variety of donor atoms can be introduced into the side chain.4 These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, β-ketoesters and simple alkenes.
  2. Pd-catalyzed, enantioselective, intramolecular α-substituted cyclic ketones: facile synthesis of functionalized chiral spirobicycles.
  3. Asymmetric boron conjugate addition of α,β-unsaturated carbonyl compounds catalyzed by
  4. CuOTf/Josiphos under non-alkaline conditions.
  5. Chiral amides via copper-catalyzed enantioselective conjugate addition.
  6. Ruthenium-catalyzed enantioselective synthesis of β-amino alcohols from 1,2-diols by “borrowing hydrogen”.
  7. Cobalt-catalyzed asymmetric addition of silylacetylenes to 1,1-disubstituted allenes.

Chemical Properties

Dark orange powder

General Description

sold in collaboration with Solvias AG

(S)-(R)-JOSIPHOS Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(R)-JOSIPHOS Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
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Shanghai Holy Biohemdeviser Co., Ltd
Tel
021-61551100
Fax
021-61551100
Country
China
ProdList
444
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Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
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61
Shanghai Incat Chemtech Co.,Ltd.
Tel
021-57603038 13601791340
Fax
021-57603057
Email
307593986@qq.com
Country
China
ProdList
475
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9649
Advantage
58
Wuhan Pengo Technology.,Ltd.
Tel
027-60707801 13628634921
Email
sunny.w@boronicgroup.com
Country
China
ProdList
146
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View Lastest Price from (S)-(R)-JOSIPHOS manufacturers

XINXIANG RUNYU MATERIAL CO., LTD.
Product
Josiphos SL-J001-2 / (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine 162291-02-3
Price
US $0.00-0.00/g
Min. Order
1KG
Purity
0.99
Supply Ability
500kg
Release date
2021-12-01
Career Henan Chemical Co
Product
di(naphthalen-1-yl)phosphine oxide 162291-02-3
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
1MT
Release date
2018-08-10

162291-02-3, (S)-(R)-JOSIPHOSRelated Search:


  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct,97% (S)-(R)-JOSIPHOS
  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct (S)-(R)-JOSIPHOS
  • Josiphos SL-J001-2 / (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
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  • (2S)-1-[(1S)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene
  • JOSIPHOS SL-J001-2
  • (S)-(+)-1-[(R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
  • (S)-1-[(1R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
  • (S,S)-1-[1-(DICYCLOHEXYLPHOSPHINO)ETHYL]-2-(DIPHENYLPHOSPHINO)FERROCENE
  • (S)-(R)-JOSIPHOS
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  • (S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]
  • (S)1 (1R)2(DIPHENYLPHOSPHINO)FERROCENYL&
  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphineethanoladduct,min.97%(S)-(R)-JOSIPHOS
  • (S)-(R)-Josiphos, Josiphos SL-J001-2, (2S)-1-[(1S)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS)
  • (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenylethyl]dicyclohexylphosphine ethanol adduct
  • (S)-(+)-1-[(R)-2-(Diphenylphospino)ferrocenyl] ethylbicyclohexylphosphine
  • 97% (S)-(R)-JOSIPHOS
  • Ferrocene, 1-[(1S)-1-(dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)-, (2S)-
  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenylethyl]dicycloh...
  • (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine [(S)-(R)-Josiphos]
  • (S)-(+)-1-[(Rp)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphineethanoladduct
  • (2Rp)-1-[(1S)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene
  • dichloromethane complex
  • 162291-02-3
  • Privileged Ligands
  • Solvias Ligands
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents
  • Chiral Phosphine
  • Ferrocene Series
  • Josiphos Series
  • organophosphine ligand