ChemicalBook > CAS DataBase List > (S)-(R)-JOSIPHOS
(S)-(R)-JOSIPHOS
Uses Reactions- Product Name
- (S)-(R)-JOSIPHOS
- CAS No.
- 162291-02-3
- Chemical Name
- (S)-(R)-JOSIPHOS
- Synonyms
- Josiphos SL-J001-2 / (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine;(S)-(R)-JOSIPHOS;JOSIPHOS SL-J001-2;97% (S)-(R)-JOSIPHOS;dichloromethane complex;(S)1 (1R)2(DIPHENYLPHOSPHINO)FERROCENYL&;(S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl];(S)1[(1R)2(diphenylphosphino)ferrocenyl] et-dicyclohexylphos;(S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenylethyl]dicycloh...;(S)-1-[(1R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
- CBNumber
- CB8268578
- Molecular Formula
- C36H44FeP210*
- Formula Weight
- 594.53
- MOL File
- 162291-02-3.mol
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(S)-(R)-JOSIPHOS Property
- alpha
- +360° (c 0.5, CHCl3)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Powder
- color
- orange
- Stability:
- store cold
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Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- F
- 10
- HS Code
- 29319090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 88718
- Product name
- (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
- Purity
- ≥97%
- Packaging
- 1g
- Price
- $682
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 88718
- Product name
- (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
- Purity
- ≥97%
- Packaging
- 5g
- Price
- $2250
- Updated
- 2023/01/07
Strem Chemicals
- Product number
- 26-1211
- Product name
- (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct, min. 97% (S)-(R)-JOSIPHOS
- Packaging
- 100mg
- Price
- $107
- Updated
- 2024/03/01
Strem Chemicals
- Product number
- 26-1211
- Product name
- (S)-(+)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ethanol adduct, min. 97% (S)-(R)-JOSIPHOS
- Packaging
- 500mg
- Price
- $375
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 88718
- Product name
- (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine
- Purity
- ≥97%
- Packaging
- 100mg
- Price
- $90.3
- Updated
- 2025/07/31
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(S)-(R)-JOSIPHOS Chemical Properties,Usage,Production
Uses
(S)-(+)-1-[(R)-2-(diphenylphosphine)ferrocene]ethyldicyclohexylphosphine is a Josiphos-class chiral ferrocene phosphine ligand, a very practical and important ligand, second only to BINAP ligands in its pioneering role. It can be used in asymmetric organic synthesis reactions such as asymmetric hydroamination of olefins and Michael addition, and has been widely used in industrial production, playing an important role in the synthesis of many pharmaceuticals and fine chemicals.
Reactions
- Ferrocenylphosphine ligands of the type cpFecp(PR2)(*CH(CH3)PR'2) are a class of asymmetric ligands developed at Solvias in Basel, Switzerland. Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products. A unique feature of these bidentate ligands is the presence of a fixed phosphine moiety and a stereogenic,functionalized side chain, which can be easily modified to accommodate electronic and steric requirements. Based on a versatile synthetic procedure starting with optically active ferrocenes of the type cpFecp(PR2)(*CH(CH3)X) [X = OAc or NR2], a variety of donor atoms can be introduced into the side chain.4 These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, β-ketoesters and simple alkenes.
- Pd-catalyzed, enantioselective, intramolecular α-substituted cyclic ketones: facile synthesis of functionalized chiral spirobicycles.
- Asymmetric boron conjugate addition of α,β-unsaturated carbonyl compounds catalyzed by
- CuOTf/Josiphos under non-alkaline conditions.
- Chiral amides via copper-catalyzed enantioselective conjugate addition.
- Ruthenium-catalyzed enantioselective synthesis of β-amino alcohols from 1,2-diols by “borrowing hydrogen”.
- Cobalt-catalyzed asymmetric addition of silylacetylenes to 1,1-disubstituted allenes.
Chemical Properties
Dark orange powder
General Description
sold in collaboration with Solvias AG
(S)-(R)-JOSIPHOS Preparation Products And Raw materials
Raw materials
Preparation Products
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(S)-(R)-JOSIPHOS Suppliers
- Tel
- 15690792173
- Fax
- 0373-7759608
- sales@runvmat.com
- Country
- China
- ProdList
- 265
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
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- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
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- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
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- China
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- 021-61551100
- Fax
- 021-61551100
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- China
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- (86) 21-58955996
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- China
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- 021-57603038 13601791340
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- 021-57603057
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- China
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- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
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- 42446
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- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
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- Advantage
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- Tel
- 027-60707801 13628634921
- sunny.w@boronicgroup.com
- Country
- China
- ProdList
- 154
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View Lastest Price from (S)-(R)-JOSIPHOS manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- (S)-(R)-JOSIPHOS 162291-02-3
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
XINXIANG RUNYU MATERIAL CO., LTD.
- Product
- Josiphos SL-J001-2 / (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine 162291-02-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 500kg
- Release date
- 2021-12-01
Career Henan Chemical Co
- Product
- di(naphthalen-1-yl)phosphine oxide 162291-02-3
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 1MT
- Release date
- 2018-08-10
162291-02-3, (S)-(R)-JOSIPHOSRelated Search:
1,3-BIS(DIMETHYLPHOSPHINO)PROPANE
JOSIPHOS SL-J011-1,JOSIPHOS SL-J011-2
(R)-(S)-JOSIPHOS,(R)-(-)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphineethanoladduct,min.97%(R)-(S)-JOSIPHOS,JOSIPHOS SL-J001-1
TRIHEXYLPHOSPHINE
TRIISOPROPYLPHOSPHINE
JOSIPHOS SL-J005-1
JOSIPHOS SL-J002-2
JOSIPHOS SL-J002-1,Josiphos SL-J002-1, (2R)-1-[(1R)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS)
JOSIPHOS SL-J009-1
DICYCLOHEXYLPHOSPHINE
Ferrocene
JOSIPHOS SL-J003-1
Josiphos SL-J004-2, (1S)-1-(Dicyclohexylphosphino)-2-[(1S)-1-(diphenylphosphino)ethyl]ferrocene (acc to CAS),JOSIPHOS SL-J004-2
(S)-(R)-JOSIPHOS
1,3-BIS(PHOSPHINO)PROPANE
JOSIPHOS SL-J418-2
JOSIPHOS SL-J013-1
Josiphos SL-J003-2, (1S)-1-(Dicyclohexylphosphino)-2-[(1S)-1-(dicyclohexylphosphino)ethyl]ferrocene (acc to CAS)