ChemicalBook > CAS DataBase List > (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
Reaction- Product Name
- (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
- CAS No.
- 155830-69-6
- Chemical Name
- (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
- Synonyms
- Josiphos SL-J002;(R)-(-)-[(S)-2-(D;JOSIPHOS SL-J002-1;(R)-(S)-PPF-P(tBu)2;-2-(Diphenylphosphino);ferrocenyl]ethyldi-tert-butylphosphine;(R)1 (1S)2(DIPHENYLPHOSPHINO)FERROCENYL&;(R)1[(1S)2(diphenylphosphino)ferrocenyl] et-di-T-butylphosph;(R)-(-)-[(S)-2-(Diphenylphosphino(ferrocenyl]ethyldi-t-butyl...;2-(1-(Di-tert-Butylphosphino)ethyl)-1-(diphenylphosphino)ferrocene
- CBNumber
- CB7229824
- Molecular Formula
- C32H40FeP2
- Formula Weight
- 542.45
- MOL File
- 155830-69-6.mol
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(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE Property
- Melting point:
- 218-220°C (dec.)
- alpha
- -412° ±15° (c 0.5, CHCl3)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform, Methanol
- form
- Powder
- color
- Orange
- InChI
- InChI=1/C27H35P2.C5H5.Fe/c1-21(29(26(2,3)4)27(5,6)7)24-19-14-20-25(24)28(22-15-10-8-11-16-22)23-17-12-9-13-18-23;1-2-4-5-3-1;/h8-21H,1-7H3;1-5H;/t21-;;/s3
- InChIKey
- STAGMXYQPGLLTD-MGIYCFTINA-N
- SMILES
- P(C1=CC=CC=C1)(C1=CC=CC=C1)[C]1[CH][CH][CH][C]1[C@@H](C)P(C(C)(C)C)C(C)(C)C.[CH]1[CH][CH][CH][CH]1.[Fe] |&1:18,r,^1:13,14,15,16,17,29,30,31,32,33|
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Safety
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25
- WGK Germany
- 3
- F
- 10
- HS Code
- 29319090
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 88719
- Product name
- (R)-1-[(SP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
- Purity
- ≥97%
- Packaging
- 1g
- Price
- $341
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 88719
- Product name
- (R)-1-[(SP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
- Purity
- ≥97%
- Packaging
- 5g
- Price
- $2009
- Updated
- 2025/07/31
TCI Chemical
- Product number
- D5438
- Product name
- (2R)-1-[(1R)-1-[Bis-tert-butylphosphino]ethyl]-2-(diphenylphosphino)ferrocene
- Packaging
- 200MG
- Price
- $99
- Updated
- 2025/07/31
Strem Chemicals
- Product number
- 26-1200
- Product name
- (R)-(-)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine, min. 97%
- Packaging
- 100mg
- Price
- $107
- Updated
- 2024/03/01
Strem Chemicals
- Product number
- 26-1200
- Product name
- (R)-(-)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi-t-butylphosphine, min. 97%
- Packaging
- 500mg
- Price
- $375
- Updated
- 2024/03/01
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(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE Chemical Properties,Usage,Production
Reaction
- Ligand for Palladium-catalyzed amination of aryl halides
- Ligand for Rhodium-catalyzed asymmetric alcoholysis and aminolysis of oxabenzonorbornadiene
- Ligand for Rhodium-catalyzed asymmetric ring opening of oxabicyclic alkenes with organoboronic acids
- Ligand for Copper-catalyzed asymmetric 1,4-hydrosilylations of α,β-unsaturated esters
- Ligand for Ruthenium-catalyzed asymmetric hydrogenation of N-sulfonated-α-dehydroamino acids
- Ligand for Rhodium-catalyzed asymmetric hydrogenation of enamines
- Ligand for Palladium-catalyzed Kumada coupling of aryl and vinyl tosylates
- Ligand for Palladium-catalyzed enantioselective synthesis of aryl sulfoxides
- Ligand for Rhodium-catalyzed enantioselective insertion of a carbenoid carbon into a C-C bond
Chemical Properties
Orange powder
Uses
It may be used as a ligand in the palladium-catalyzed alkoxycarbonylation of 6-bromo-1,4-benzodioxane with sodium tert-butoxide to form the corresponding tert-butyl ester.
General Description
(R)-1-[(SP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine (PPF-tBu) is a chiral ferrocenyl diphosphine ligand.
Synthesis
(1) Synthesis of (R)-1-ferrocenyl ethyl di-tert-butylphosphine
Under argon protection, vinyl ferrocene (1 mol, 212 g), (R)-3,3'-bis(3,5-dimethylphenyl)-1,1'-binaphthol phosphonate (0.01 mol, 5.6g) and 1L of toluene, then add di-tert-butylphosphine (1 mol, 147g), heating to 60 ?? reaction for 12 hours, and then cool down and cool down, to the system dropwise addition of water, and then partitioning, the organic layer with anhydrous magnesium sulfate drying, filtration, distillation under reduced pressure to remove the solvent to get a yellow solid, dichloromethane and methanol recrystallization to get (R)-1 - ferrocenylethyl di-tert-butylphosphine 347g, yield 97%, e.e. value 99.5%.
(2) Synthesis of (R)-(-)-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
Under the protection of argon, (R)-1-ferrocenyl ethyldi-tert-butylphosphine (0.9 mol, 321 g) and 1 L of ethyl ether were added to a dry reactor, and then a 1 M diethylzinc hexane solution (0.9 mol, 0.9 L ), after the reaction at 0??C for 3 hours, diphenylphosphonium chloride (0.9 mol, 199 g) was added dropwise to the system, and after the dropwise addition was completed, it was heated and refluxed for 2 hours, and quenched by adding water to the system, and then partitioned, and the organic layer was dried with anhydrous magnesium sulfate, filtered, and the yellow solid was obtained after the solvent was removed by distillation under reduced pressure, and recrystallized from methylene chloride and methanol to obtain (R)-(-)-1-[(S)-2- diphenylphosphine Ferrocene ethyl-di-tert-butylphosphorus 468g, yield 96%, e.e. value 99.3%.
(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE Preparation Products And Raw materials
Raw materials
Acetic anhydride
2-Chloro-2-methylpropane
Potassium carbonate
Chlorodiphenylphosphine
Phosphorus trichloride
(R)-(+)-N,N-DIMETHYL-1-FERROCENYLETHYLAMINE
Ethyl acetate
Lithium Aluminum Hydride
Hydrochloric acid
Dichloromethane
Acetic acid
Magnesium
n-Butyllithium
Preparation Products
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(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE Suppliers
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View Lastest Price from (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- (R)-(-)-[(S)-2-(Diphenylphosphino(ferrocenyl]ethyldi-tert-butylphosphine 155830-69-6
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
XINXIANG RUNYU MATERIAL CO., LTD.
- Product
- (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE 155830-69-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1KG
- Purity
- 0.97
- Supply Ability
- 500kg
- Release date
- 2021-11-30
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- (R)-1-[(SP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine 155830-69-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
155830-69-6, (R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINERelated Search:
(R)-(-)-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI(3,5-DIMETHYLPHENYL)PHOSPHINE
(R)-(-)-1-[(S)-2-(DICYCLOHEXYLPHOSPHINO)FERROCENYL]ETHYLDI-T-BUTYLPHOSPHINE
(R)-1-[(R)-2-[2-(DIPHENYLPHOSPHINO)PHENYL]-FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
(R)-1-[(1S)-2-(DICYCLOHEXYLPHOSPHINO)FERROCENYL]ETHYLDICYCLOHEXYLPHOSPHINE
(R)-(S)-JOSIPHOS
1,3-BIS(DIMETHYLPHOSPHINO)PROPANE
T-BUTYLPHOSPHINE
(R)-1-[(S)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE
(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
Di-tert-butylphosphine
(S)-1-[(1R)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
TRIISOPROPYLPHOSPHINE
Ferrocene
DI-T-BUTYL(I-PROPYL)PHOSPHINE
(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine
TERT-BUTYLDIISOPROPYLPHOSPHINE
(R)-1-[(S)-2-[BIS(4-METHOXY-3,5-DIMETHYLPHENYL)PHOSPHINO]FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
(R)-1-[(S)-2-[DI(1-NAPHTHYL)PHOSPHINO]FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE