ChemicalBook > CAS DataBase List > 2-Chloro-2-methylpropane

2-Chloro-2-methylpropane

Product Name
2-Chloro-2-methylpropane
CAS No.
507-20-0
Chemical Name
2-Chloro-2-methylpropane
Synonyms
TERT-BUTYL CHLORIDE;T-BUTYL CHLORIDE;2-METHYL-2-CHLOROPROPANE;2-methyl-2-propylchloride;1-Chloro-1,1-dimethylethane;Tert-Butyl chloride (2-chlor-2-methylpropan);tert-butyl chloride/2-chloro-2-methylpropane;tert-C4H9Cl;oro-2-methyL;tert-Butylchlorid
CBNumber
CB3372184
Molecular Formula
C4H9Cl
Formula Weight
92.57
MOL File
507-20-0.mol
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2-Chloro-2-methylpropane Property

Melting point:
-25 °C (lit.)
Boiling point:
51-52 °C (lit.)
Density 
0.851 g/mL at 25 °C (lit.)
vapor density 
3.2 (vs air)
vapor pressure 
4.82 psi ( 20 °C)
refractive index 
n20/D 1.385(lit.)
Flash point:
−10 °F
storage temp. 
Store at <= 20°C.
solubility 
soluble in Chloroform
form 
Liquid
color 
Clear
explosive limit
1.8-10.1%(V)
Water Solubility 
SLIGHTLY SOLUBLE
Merck 
14,1562
BRN 
1730872
Dielectric constant
10.949999999999999
Stability:
Stable. Extremely flammable. Note low flash point. Incompatible with strong oxidizing agents. Vapour, being much denser than air, may travel considerable distances to a source of ignition. Hygroscopic.
InChIKey
NBRKLOOSMBRFMH-UHFFFAOYSA-N
LogP
2.45 at 20-25℃
CAS DataBase Reference
507-20-0(CAS DataBase Reference)
NIST Chemistry Reference
Propane, 2-chloro-2-methyl-(507-20-0)
EPA Substance Registry System
tert-Butyl chloride (507-20-0)
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Safety

Hazard Codes 
F
Risk Statements 
11
Safety Statements 
16-29-33-7/9-9
RIDADR 
UN 1127 3/PG 2
WGK Germany 
1
RTECS 
TX5040000
Autoignition Temperature
570°C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29031980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.01550
Product name
2-Chloro-2-methylpropane
Purity
for synthesis
Packaging
100ML
Price
$37.3
Updated
2024/03/01
Sigma-Aldrich
Product number
8.01550
Product name
2-Chloro-2-methylpropane
Purity
for synthesis
Packaging
1L
Price
$97.1
Updated
2024/03/01
Sigma-Aldrich
Product number
19780
Product name
2-Chloro-2-methylpropane
Purity
puriss. p.a., ≥99.0% (GC)
Packaging
250ml
Price
$48.5
Updated
2024/03/01
Sigma-Aldrich
Product number
19780
Product name
2-Chloro-2-methylpropane
Purity
puriss. p.a., ≥99.0% (GC)
Packaging
1l
Price
$102
Updated
2024/03/01
TCI Chemical
Product number
C0208
Product name
2-Chloro-2-methylpropane
Purity
>98.0%(GC)
Packaging
25mL
Price
$16
Updated
2024/03/01
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2-Chloro-2-methylpropane Chemical Properties,Usage,Production

Chemical Properties

tert-Butyl chloride is a colourless liquid. Miscible with alcohol and ether, insoluble in water. It is flammable and releases toxic phosgene when heated. Reacts violently with oxidizing agents. More toxic than 1-chlorobutane. tert-Butyl Chloride has a wide range of applications in the fields of medicine, pesticides, rubber, plastic additives and other chemical industries.

Uses

2-Chloro-2-methylpropane is an alkylating agent that is used to functionalize molecules with tert-butyl group.
It serves as an effective chlorinating agent, in combination with the ionic liquid, 1-butyl-3-methylimidazolium bromide for converting alcohols into chlorides.
It can also be used to prepare tert-butyl ethers by treating with corresponding alcohols.

Application

tert-Butyl chloride plays an important role as a starting material to perform nucleophilic substitution reactions in order to prepare alcohol and alkoxides salts. It is used as an alkylating agent for the introduction of tert-butyl group and is also involved in Friedel-Crafts reactions. It is employed as an intermediate for the synthesis of agrochemicals and pharmaceuticals.

Flammability and Explosibility

Flammable

Safety Profile

Questionable carcinogen with experimental neoplastigenic data. Dangerous fire hazard when exposed to heat, flame (sparks), and oxidlzers. To fight fue, use water, spray, fog, alcohol foam, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORINATED HYDROCARBONS, ALIPHATIC.

Synthesis

tert-Butyl chloride is prepared from tertbutyl alcohol (tert-butanol) using an acid catalyzed dehydration reaction.

The first step of the overall reaction is an acid-base reaction between the t-butanol and the hydrochloric acid. The t-butanol is a weak base and the hydrochloric acid is a strong acid. The alcoholic oxygen becomes fully protonated and so the equilibrium lies far to the right. In the second step we have the slow loss of water to form a carbocation intermediate. This species is very reactive and is immediately attacked by the chloride ion liberated in the first step to form tert-Butyl chloride.

Purification Methods

Purification methods commonly used for other alkyl halides lead to decomposition. Some impurities can be removed by photochlorination with a small amount of chlorine prior to use. The liquid is washed with ice water, dried with CaCl2 or CaCl2 + CaO and fractionally distilled. It has been further purified by repeated fractional crystallisation by partial freezing. [Beilstein 1 IV 288.]

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2-Chloro-2-methylpropane Suppliers

Shandong Tongcheng Medicine Co., Ltd.
Tel
13721975233
Email
1040955529@qq.com
Country
China
ProdList
20
Advantage
58
Shanghai Huafutai Chemical Co., Ltd
Tel
13906215003 13906215003
Email
13906215003@163.com
Country
China
ProdList
236
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
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62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
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View Lastest Price from 2-Chloro-2-methylpropane manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-Chloro-2-methylpropane 507-20-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-12-03
Baoji Guokang Bio-Technology Co., Ltd.
Product
2-Chloro-2-methylpropane 507-20-0
Price
US $4761.00/T
Min. Order
1T
Purity
99%
Supply Ability
20T
Release date
2021-06-02
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Chloro-2-methylpropane 507-20-0
Price
US $5.00/KG
Min. Order
1KG
Purity
96%
Supply Ability
100tons
Release date
2024-08-16

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