DIF-3
- Product Name
- DIF-3
- CAS No.
- 113411-17-9
- Chemical Name
- DIF-3
- Synonyms
- DIF-3, 10 mM in DMSO;DIF-3 >=99% (HPLC), solid;1-(3-Chloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one;1-Hexanone, 1-(3-chloro-2,6-dihydroxy-4-methoxyphenyl)-;1-(3-Chloro-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone, Differentiation-inducing factor 3
- CBNumber
- CB4498007
- Molecular Formula
- C13H17ClO4
- Formula Weight
- 272.72
- MOL File
- 113411-17-9.mol
DIF-3 Property
- Boiling point:
- 416.9±45.0 °C(Predicted)
- Density
- 1.240±0.06 g/cm3(Predicted)
- solubility
- DMSO: 46 mg/mL, soluble
- form
- solid
- pka
- 5.92±0.45(Predicted)
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- D0567
- Product name
- DIF-3
- Purity
- ≥99% (HPLC), solid
- Packaging
- 1mg
- Price
- $131
- Updated
- 2024/03/01
- Product number
- 0324AQ
- Product name
- DIF-3
- Packaging
- 1mg
- Price
- $188
- Updated
- 2021/12/16
- Product number
- MTB0000064
- Product name
- DIF-3
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $554.23
- Updated
- 2021/12/16
- Product number
- MTB0000064
- Product name
- DIF-3
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $1298.86
- Updated
- 2021/12/16
- Product number
- MTB0000064
- Product name
- DIF-3
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $1593.9
- Updated
- 2021/12/16
DIF-3 Chemical Properties,Usage,Production
Uses
DIF-3 has been used: as a glycogen synthase kinase-3β (GSK-3β) activator to determine if GSK-3β is required for the anti-inflammatory actions of VU0360172 (VuPAM) in murine microglia, as a phosphorylation inhibitor for GSK-3β to examine the links between activation of protein kinase B (PKB)/GSK-3β/Fyn axis and nuclear factor erythroid 2–related factor 2 (NRF2) retention, as a GSK3β activator to study its effects on the cyclooxygenase 2 (COX2) expression levels in human primary chondrocytes in response to visfatin, as a GSK3β activator to study its effects on the intracellular mechanics along with F-actin and β-tubulin fiber networks in human primary chondrocytes
Biological Activity
Differentiation-inducing factor-3 (DIF-3) prevents the proliferation of intestinal cancer cells in vitro and in vivo. It may serve as a novel anti-cancer agent.', 'DIF-3 Inhibits cell cycle by inducing G0/G1 arrest.
DIF-3 Preparation Products And Raw materials
Raw materials
Preparation Products
DIF-3 Suppliers
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