N-(2-nitrophenyl)-2-fluoroaniline
- Product Name
- N-(2-nitrophenyl)-2-fluoroaniline
- CAS No.
- 28898-02-4
- Chemical Name
- N-(2-nitrophenyl)-2-fluoroaniline
- Synonyms
- 2-Fluoro-2'-nitrodiphenylamine;N-(2-nitrophenyl)-2-fluoroaniline;N-(2-fluorophenyl)-2-nitroaniline;2-Fluoro-N-(2-nitrophenyl)aniline;2-[(2-Fluorophenyl)amino]nitrobenzene;Benzenamine, 2-fluoro-N-(2-nitrophenyl)-;2-[(2-Fluorophenyl)amino]nitrobenzene 98%;2-FLUORO-2'-NITRODIPHENYLAMINE ISO 9001：2015 REACH;2-Fluoro-N-(2-nitrophenyl)aniline, 2-Fluoro-2'-nitrodiphenylamine
- CBNumber
- CB4501121
- Molecular Formula
- C12H9FN2O2
- Formula Weight
- 232.21
- MOL File
- 28898-02-4.mol
Safety
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F621943
- Product name
- 2-Fluoro-2''-nitrodiphenylamine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- F621943
- Product name
- 2-Fluoro-2''-nitrodiphenylamine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 4655-3-22
- Product name
- 2-Fluoro-2'-nitrodiphenylamine
- Purity
- 98%
- Packaging
- 5G
- Price
- $65
- Updated
- 2021/12/16
- Product number
- PC3545
- Product name
- 2-[(2-Fluorophenyl)amino]nitrobenzene
- Purity
- 98%
- Packaging
- 5g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 4655-3-22
- Product name
- 2-Fluoro-2'-nitrodiphenylamine
- Purity
- 98%
- Packaging
- 25g
- Price
- $195
- Updated
- 2021/12/16
N-(2-nitrophenyl)-2-fluoroaniline Chemical Properties,Usage,Production
Synthesis
348-54-9
1493-27-2
28898-02-4
GENERAL METHOD: Suspend NaH (75 mmol) in DMF (60 mL) at 0°C and slowly add o-fluoroaniline (50 mmol). After maintaining 0°C and stirring for 30 min, a solution of 1-fluoro-2-nitrobenzene (60 mmol) in DMF (30 mL) was added dropwise. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. Upon completion of the reaction, the mixture was carefully poured into stirred saturated NH4Cl solution (500 mL) to quench the reaction. The precipitate was collected by filtration, the filter cake was washed with water and finally purified by recrystallization from methanol to afford the target product 2-fluoro-N-(2-nitrophenyl)aniline (15j). The product was a red solid with a yield of 74.1% and a melting point of 74.4-75.8 °C. 1H NMR (400 MHz, DMSO-d6) δ 9.28 (s, 1H), 8.14 (d, J = 8.0 Hz, 1H), 7.51 (m, 2H), 7.35 (m, 3H), 6.90 (m, 2H); MS (ESI) m/z (%). 231.1 [M-H]-.
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 16, p. 4475 - 4486
[2] Molecules, 2015, vol. 20, # 1, p. 1712 - 1730
[3] Archiv der Pharmazie, 1997, vol. 330, # 11, p. 353 - 357
[4] Patent: WO2008/73459, 2008, A1. Location in patent: Page/Page column 95
[5] Journal of Medicinal Chemistry, 2010, vol. 53, # 11, p. 4511 - 4521
N-(2-nitrophenyl)-2-fluoroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
N-(2-nitrophenyl)-2-fluoroaniline Suppliers
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- Country
- India
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View Lastest Price from N-(2-nitrophenyl)-2-fluoroaniline manufacturers
- Product
- 2-FLUORO-2'-NITRODIPHENYLAMINE 28898-02-4
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-03