POLY-L-HISTIDINE HYDROCHLORIDE MW
- Product Name
- POLY-L-HISTIDINE HYDROCHLORIDE MW
- CAS No.
- 26062-48-6
- Chemical Name
- POLY-L-HISTIDINE HYDROCHLORIDE MW
- Synonyms
- polyhistidine;poly-L-histidine chloride;poly-L-HistidineMW5000-15000;POLY-L-HISTIDINE MOL WT 5000-15000;POLY-L-HISTIDINE HYDROCHLORIDE MW;Poly-L-histidine mol wt 5,000-25,000;POLY-L-HISTIDINE, HYDROCHLORIDE*MW 15,00 0-50,000
- CBNumber
- CB4504157
- Molecular Formula
- C6H9N3O2
- Formula Weight
- 155.16
- MOL File
- 26062-48-6.mol
POLY-L-HISTIDINE HYDROCHLORIDE MW Property
- storage temp.
- -20°C
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- P9386
- Product name
- Poly-L-histidine
- Purity
- mol wt 5,000-25,000
- Packaging
- 10mg
- Price
- $157
- Updated
- 2024/03/01
- Product number
- P9386
- Product name
- Poly-L-histidine
- Purity
- mol wt 5,000-25,000
- Packaging
- 50mg
- Price
- $437
- Updated
- 2024/03/01
- Product number
- P9386
- Product name
- Poly-L-histidine
- Purity
- mol wt 5,000-25,000
- Packaging
- 100mg
- Price
- $805
- Updated
- 2024/03/01
POLY-L-HISTIDINE HYDROCHLORIDE MW Chemical Properties,Usage,Production
Uses
Poly-L-histidine has been used:
- as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)
- as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane
- in screening its anti-prion activity in cell based and in vivo anti-prion assay
Definition
ChEBI: Histidine is an alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. It has a role as a metabolite. It is an alpha-amino acid, a member of imidazoles, an aromatic amino acid and a polar amino acid. It contains a 1H-imidazol-4-ylmethyl group. It is a conjugate base of a histidinium(1+). It is a conjugate acid of a histidinate(1-).
General Description
Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonation?deprotonation.
Biochem/physiol Actions
Poly-L-histidine (Phis) copolymers are biocompatible, pH responsive and are less toxic. It exhibits endolysosomal escape funcationality. The copolymer of Phis with poly(ethylene glycol)?poly(d,l-lactide) (PEG-PLA) is effective in delivering doxorubicin. pH sensitive poly(l-histidine) copolymer micelles have application in delivering anticancer drugs in acidic microenvironment.
POLY-L-HISTIDINE HYDROCHLORIDE MW Preparation Products And Raw materials
Raw materials
Preparation Products
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