ChemicalBook > CAS DataBase List > JWG-071

JWG-071

Product Name
JWG-071
CAS No.
2250323-50-1
Chemical Name
JWG-071
Synonyms
JWG-071;JWG 071,JWG071;JWG-071, 10 mM in DMSO;11-(sec-Butyl)-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl-11-(1-methylpropyl)-
CBNumber
CB45544730
Molecular Formula
C34H44N8O3
Formula Weight
612.77
MOL File
2250323-50-1.mol
More
Less

JWG-071 Property

Boiling point:
801.7±75.0 °C(Predicted)
Density 
1.238±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
8.14±0.42(Predicted)
form 
Solid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2541
Product name
JWG-071
Purity
≥98% (HPLC)
Packaging
5MG
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2541
Product name
JWG-071
Purity
≥98% (HPLC)
Packaging
25MG
Price
$380
Updated
2024/03/01
ChemScene
Product number
CS-8155
Product name
JWG-071
Purity
98.55%
Packaging
5mg
Price
$708
Updated
2021/12/16
DC Chemicals
Product number
020507
Product name
JWG-071
Packaging
001
Price
$350
Updated
2021/12/16
More
Less

JWG-071 Chemical Properties,Usage,Production

Biological Activity

JWG-071 is the first reported ERK5 kinase-selective chemical probe which can increases ERK5 activity and BRD4 selectivity. It will be a much-needed chemical probe for deconvoluted ERK5 and BRD4 pharmacology.

in vitro

JWG-071 inhibits ERK5 and LRRK2 with IC 50 of 88 and 109 nM, respectively.

< /div>

target

ERK5

88 nM (IC 50 )

JWG-071 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

JWG-071 Suppliers

China 29 United States 3 Global 32
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9805
Advantage
58
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1925
Advantage
55
Tel
15861130028; 15861130028
Email
956912955@qq.com
Country
China
ProdList
288
Advantage
58
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Tel
15195022192
Email
279776773@qq.com
Country
China
ProdList
2011
Advantage
58
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Tel
020-82000279 18988968278
Fax
QQ：3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58

2250323-50-1, JWG-071Related Search:


  • JWG-071
  • 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl-11-(1-methylpropyl)-
  • JWG 071,JWG071
  • 11-(sec-Butyl)-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
  • JWG-071, 10 mM in DMSO
  • 2250323-50-1
  • C34H44N8O3