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Boc-Val-Ala-PAB

Product Name
Boc-Val-Ala-PAB
CAS No.
1884577-99-4
Chemical Name
Boc-Val-Ala-PAB
Synonyms
Boc-Val-Ala-PAB;L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;(S)-2-(Boc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide;tert-butyl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate;tert-butyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate;tert-Butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
CBNumber
CB45864430
Molecular Formula
C20H31N3O5
Formula Weight
393.48
MOL File
1884577-99-4.mol
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Boc-Val-Ala-PAB Property

Boiling point:
653.7±55.0 °C(Predicted)
Density 
1.166±0.06 g/cm3(Predicted)
form 
Solid
pka
11.26±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Iris Biotech GmbH
Product number
ADC1040
Product name
Boc-Val-Ala-PAB
Packaging
250mg
Price
$303.75
Updated
2021/12/16
Iris Biotech GmbH
Product number
ADC1040
Product name
Boc-Val-Ala-PAB
Packaging
1g
Price
$877.5
Updated
2021/12/16
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Boc-Val-Ala-PAB Chemical Properties,Usage,Production

Description

Boc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Boc-Val-Ala-PAB Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Val-Ala-PAB Suppliers

Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
18478
Advantage
58
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View Lastest Price from Boc-Val-Ala-PAB manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Boc-Val-Ala-PAB 1884577-99-4
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-29

1884577-99-4, Boc-Val-Ala-PABRelated Search:


  • Boc-Val-Ala-PAB
  • (S)-2-(Boc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide
  • tert-Butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
  • L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-
  • tert-butyl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate
  • tert-butyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
  • 1884577-99-4
  • Linker