ChemicalBook > CAS DataBase List > 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE

Product Name
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
CAS No.
292606-35-0
Chemical Name
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
Synonyms
N-Boc-2,2-dimethyl-1,3-propanediamine;N-Boc-2,2-dimethyl-1,3-diaminopropane;BOC-1-AMINO-2,2-DIMETHYL-1,3-PROPYLDIAMINE;1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE;tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate;tert-Butyl N-(3-amino-2,2-dimethylpropyl)carbamate;(S)-(+)-5-1-Boc-amino-2,2-dimethyl-1,3-propanediamine;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine;(3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >
CBNumber
CB4666820
Molecular Formula
C10H22N2O2
Formula Weight
202.29
MOL File
292606-35-0.mol
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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Property

Melting point:
74 °C
Boiling point:
293.8±23.0 °C(Predicted)
Density 
0.964±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
pka
12.86±0.46(Predicted)
form 
powder to crystal
color 
White to Almost white
CAS DataBase Reference
292606-35-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2924.19.8000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3052
Product name
N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$51
Updated
2025/07/31
TCI Chemical
Product number
B3052
Product name
N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$248
Updated
2025/07/31
TRC
Product number
B789250
Product name
tert-Butyl(3-Amino-2,2-dimethylpropyl)carbamate
Packaging
100mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB149670
Product name
1-Boc-amino-2,2-dimethyl-1,3-propanediamine
Packaging
250mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB149670
Product name
1-Boc-amino-2,2-dimethyl-1,3-propanediamine
Packaging
1g
Price
$259
Updated
2021/12/16
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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Chemical Properties,Usage,Production

Synthesis

7328-91-8

24424-99-5

292606-35-0

Di-tert-butyl dicarbonate was slowly added to a solution of 2,2-dimethylpropane-1,3-diamine in dichloromethane (DCM) (500 mL) of 2,2-dimethylpropane-1,3-diamine (80 g, 783 mmol) and di-tert-butyl dicarbonate (91 mL, 391 mmol) at 0 °C. The reaction mixture was stirred at ambient temperature for 12 hours. Subsequently, the reaction mixture was concentrated to remove the solvent. The crude product was purified by column chromatography (neutral alumina) using methanol: dichloromethane (1:9) as eluent to afford tert-butyl (3-amino-2,2-dimethylpropyl)carbamate (50 g, 247 mmol, 31.6% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 0.85 (s, 6H), 1.44 (s, 9H), 2.35-2.52 (m, 2H), 3.00 (br d, J = 6.14Hz, 2H), 5.16 (br s, 1H).

References

[1] Patent: WO2018/109648, 2018, A1. Location in patent: Page/Page column 64
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 2, p. 236 - 246
[3] Patent: US2005/20623, 2005, A1. Location in patent: Page 116
[4] Patent: EP1550657, 2005, A1. Location in patent: Page/Page column 46

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Suppliers

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View Lastest Price from 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE manufacturers

Career Henan Chemical Co
Product
tert-Butyl (3-amino-2,2-dimethylpropyl)carbamate 292606-35-0
Price
US $1.00/g
Min. Order
1g
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-07

292606-35-0, 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINERelated Search:

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate 2,7-DIAZA-SPIRO[4.4]NONANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Carbamic acid, (7S)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI) 2,2-DIMETHYL-1,3-PROPANEDIAMINE TERT-BUTYL 2,7-DIAZASPIRO[4.5]DECANE-2-CARBOXYLATE 2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLIC ACID T-BUTYL ESTER Carbamic acid, (3-azabicyclo[3.1.0]hex-1-ylmethyl)-, 1,1-dimethylethyl ester Carbamic acid, 5-azaspiro[2.4]hept-1-yl-, 1,1-dimethylethyl ester (9CI) Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate TERT-BUTYL 2,8-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE 2-OXO-1,2-DIHYDRO-SPIRO[INDOLE-3,3'-PYRROLIDINE]-1'-CARBOXYLIC ACID TERT-BUTYL ESTER Tert-butyl 2,6-diazaspiro[3.4]octane-6-carboxylate TERT-BUTYL 4-[(2-METHOXYETHYL)AMINO]-3,3-DIMETHYLPIPERIDINE-1-CARBOXYLATE 3-[N-(4-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE (1-IMIDAZOL-1-YLMETHYL-CYCLOPROPYLMETHYL)-CARBAMIC ACID TERT-BUTYL ESTER 3-[N-(2-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE 3-[N-(3-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE

  • tert-Butyl N-(3-amino-2,2-dimethylpropyl)carbamate
  • N-Boc-2,2-dimethyl-1,3-diaminopropane
  • CarbaMic acid, N-(3-aMino-2,2-diMethylpropyl)-, 1,1-diMethylethyl ester
  • N-Boc-2,2-dimethyl-1,3-propanediamine tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate (3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester N-Boc-2,2-dimethyl-1,3-diaminopropane
  • <i>N</i>-(<i>tert</i>-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
  • 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
  • BOC-1-AMINO-2,2-DIMETHYL-1,3-PROPYLDIAMINE
  • (3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester
  • N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
  • N-Boc-2,2-dimethyl-1,3-propanediamine
  • tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate
  • Carbamic acid, (3-amino-2,2-dimethylpropyl)-, 1,1-dimethylethyl ester (9CI)
  • (S)-(+)-5-1-Boc-amino-2,2-dimethyl-1,3-propanediamine
  • N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine &gt
  • 292606-35-0
  • AMIDE
  • Monoprotected Diaminoalkanes
  • N-Boc-diaminoalkanes
  • N-BOC
  • pharmacetical