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Polyoxyethylene lauryl ether

Description Reference
Product Name
Polyoxyethylene lauryl ether
CAS No.
9002-92-0
Chemical Name
Polyoxyethylene lauryl ether
Synonyms
Lauryl alcohol ethoxylate;lauromacrogol;Fatty alcohol polyoxyethylene ether;laureth;ped;thesit;Brij L23;AEO4;LAURETH-25;Macrogol lauryl ether
CBNumber
CB4688466
Molecular Formula
C58H118O24
Formula Weight
1199.55
MOL File
9002-92-0.mol
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Polyoxyethylene lauryl ether Property

Melting point:
41-45 °C(lit.)
Boiling point:
100 °C(lit.)
Density 
0.99 g/mL±0.002 g/mL at 20 °C
vapor pressure 
<1 mm Hg ( 20 °C)
refractive index 
n20/D 1.461
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
H2O: 40 mg/mL at 20 °C, clear, colorless
form 
Waxy Pellets
pka
0[at 20 ℃]
color 
White
PH
5.5-7.0 (100g/l, H2O, 20℃)
Odor
Odorless
PH Range
5.5 - 7.5
Water Solubility 
soluble
FreezingPoint 
35.0 to 40.0 ℃
Merck 
14,7558
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
2.26 at 25℃
EPA Substance Registry System
Polyethylene glycol monododecyl ether (9002-92-0)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-41-36/37/38-38-37/38-36
Safety Statements 
26-39-37/39-36/37/39-36-24/25
RIDADR 
UN 3082 9/PG 3
WGK Germany 
3
RTECS 
MD0875000
3
TSCA 
Yes
HS Code 
34021300
HS Code 
38220000
Hazardous Substances Data
9002-92-0(Hazardous Substances Data)
Toxicity
LD50 in mice (mg/kg): 1170 orally, 125 i.v. (Zipf)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.01962
Product name
Brij? 35
Purity
forsynthesis
Packaging
250g
Price
$33.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.01962
Product name
Brij? 35
Purity
forsynthesis
Packaging
1kg
Price
$116
Updated
2024/03/01
Sigma-Aldrich
Product number
16005
Product name
Brij® L23
Purity
main component: tricosaethylene glycol dodecyl ether
Packaging
250g
Price
$59.8
Updated
2024/03/01
Sigma-Aldrich
Product number
16005
Product name
Brij® L23
Purity
main component: tricosaethylene glycol dodecyl ether
Packaging
1kg
Price
$139
Updated
2024/03/01
Sigma-Aldrich
Product number
205534
Product name
C₁₂E₉, PROTEIN GRADE® Detergent, 10% Solution
Purity
A non-ionic detergent useful for the solubilization of membrane-bound proteins in their native state. HLB number: 13.6. Note: 1 set = 5 x 10 ml.
Packaging
1SET
Price
$357
Updated
2022/05/15
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Polyoxyethylene lauryl ether Chemical Properties,Usage,Production

Description

As a non-ionic surfactant, polyoxyethylene lauryl ether has excellent washing, emulsifying, dispersing, wetting, and solubilizing functions. It also shows strong foaming ability, easy rinsing performance, and excellent detergency. Because this substance acts as one of the lowest irritant species among various surfactants, it is often selected as raw material for mild detergents, shampoos (such as baby shampoos), bath lotion, cleansing milk, and cosmetics. In addition, this chemical may function as emulsifier, softener, wetting agent, and foaming agent. In terms of solubilizing function, this product has been demonstrated to assist in solubilization of steroid hormones, benzoic acid derivatives, and barbiturates.1-3 Besides, when used as surfactant emulsifier, polyoxyethylene lauryl ether is proved to be an active agent for preparing nanoemulsions for food applications.4

Reference

  1. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF STEROID-HORMONES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2832-2837.
  2. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF BENZOIC-ACID DERIVATIVES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2824-2831.
  3. Ikeda, K.; Kato, K.; Tukamoto, T., SOLUBILIZATION OF BARBITURATES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1971, 19, 2510-+.
  4. Silva, H. D.; Cerqueira, M. A.; Vicente, A. A., Nanoemulsions for Food Applications: Development and Characterization. Food Bioprocess Technol. 2012, 5, 854-867.

Chemical Properties

White or almost white, unctuous and hygroscopic mass, melting at 24 °C into a colourless or yellowish, viscous liquid.

Uses

Brij L23 is a a pharmaceutical compound used in the schlerotherapy treatments, in those suffering from blood vessel malformations and mutations.

Uses

Solvent; nonionic emulsifier; pharmaceutic aid (surfactant); spermaticide.

Uses

Ethosperse(R) LA-4 is a medium range HLB, ethoxylated, nonionic ether of lauryl alcohol with broad range pH stability. It is suggested for use as an emulsifier in cosmetics to add body and texture (humectant), in household products and in lubricants.

Production Methods

The method for producing a Polyoxyethylene Lauryl Ether, which comprises a sulfation step wherein an ethylene oxide addition product of an alkyl alcohol having 8-22 carbon atoms is reacted with an SO3-containing gas, thereby obtaining a sulfated product of the ethylene oxide addition product, and a neutralization step wherein the sulfated product is neutralized, thereby obtaining a sulfate. The ethylene oxide addition product contains from 0.01% by mass to 1% by mass (inclusive) of an alkali metal hydroxide relative to the total mass of the ethylene oxide addition product.

brand name

Brij 30 (ICI Americas).

General Description

Clear colorless to light yellow viscous liquid. Colorless at 266°F; brown at 644°F. Bland odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

Polyoxyethylene lauryl ether is incompatible with strong oxidizing agents and strong bases.

Fire Hazard

Polyoxyethylene lauryl ether is combustible.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Brij? L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.

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View Lastest Price from Polyoxyethylene lauryl ether manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Polyethylene Glycol Monododecyl Ether 9002-92-0
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-06-03
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Polyoxyethylene Lauryl Ether 9002-92-0
Price
US $90.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Fatty alcohol polyoxyethylene ether
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500kg/month
Release date
2021-08-20

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