SB 221284

Product Name: SB 221284
CAS No.: 196965-14-7
Chemical Name: SB 221284
Synonyms: SB 221284;5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE;2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE;1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
CBNumber: CB4704933
Molecular Formula: C16H14F3N3OS
Formula Weight: 353.36
MOL File: 196965-14-7.mol

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SB 221284 Property

Melting point:: 262-264 °C
Boiling point:: 536.2±50.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO: ~14 mg/mL, soluble
pka: 13.13±0.20(Predicted)
form: solid
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1379
Product name: SB221284
Purity: ≥99%(HPLC)
Packaging: 10
Price: $96
Updated: 2021/12/16

Tocris

Product number: 1379
Product name: SB221284
Purity: ≥99%(HPLC)
Packaging: 50
Price: $400
Updated: 2021/12/16

TRC

Product number: S155028
Product name: SB221284
Packaging: 5mg
Price: $170
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000723
Product name: SB 221284
Purity: 95.00%
Packaging: 10MG
Price: $709.46
Updated: 2021/12/16

ApexBio Technology

Product number: B6713
Product name: SB221284
Packaging: 50mg
Price: $786
Updated: 2021/12/16

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SB 221284 Chemical Properties,Usage,Production

Uses

SB 221284 is a potent, selective SR-2C/SR-2B antagonist.

Definition

ChEBI: SB 221284 is an indolyl carboxylic acid.

Biological Activity

Potent, selective 5-HT 2C/2B receptor antagonist. pK i values are 6.4, 7.9 and 8.6 for 5-HT 2A , 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo .

SB 221284 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 221284 Suppliers

China 16 Germany 1 Switzerland 1 United Kingdom 4 United States 10 USA 1 Global 33

3B Pharmachem (Wuhan) International Co.,Ltd.

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Energy Chemical

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TargetMol Chemicals Inc.

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Nantong QuanYi Biotechnology Co., Ltd

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Qingdao Jieshikang Biotechnology Co., Ltd.

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Shanghai Chaoyan Biotechnology Co., Ltd.

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Beijing Bolide Biotechnology Co., Ltd.

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Beijing Fubo Biotechnology Co., Ltd.

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Guangzhou WeiBo Chemical Co., Ltd.

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Shanghai PI Chemicals Ltd.

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196965-14-7, SB 221284Related Search:

2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 2-(TRIFLUOROMETHYL)THIOPHENOL 6-METHYL-2,3-DIHYDRO-1H-INDOLE 6-(Trifluoromethyl)indoline SB 221284 4-METHYLTHIO-3-(TRIFLUOROMETHYL)ANILINE

5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE

2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE

SB 221284

1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-

196965-14-7

C16H14N3F3OS