ChemicalBook > CAS DataBase List > H-(2S,4R)-GAMMA-HYDROXY-GLU-OH

H-(2S,4R)-GAMMA-HYDROXY-GLU-OH

Product Name
H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
CAS No.
2485-33-8
Chemical Name
H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
Synonyms
H-(2S,4R)-Glu(g-OH)-OH;H-(2S,4R)-g-Hydroxy-Glu-OH;H-(2S,4R)-GLU(GAMMA-OH)-OH;H-(2S,4R)-γ-Hydroxy-Glu-OH;H-(2S,4R)-GAMMA-HYDROXY-GLU-OH;(4R)-4-Hydroxy-L-glutaMic Acid;erythro-4-Hydroxy-L-glutaMic Acid;(2S,4R)-4-Hydroxy-L-glutaMic Acid;(2S,4R)-γ-Hydroxy-L-glutamic acid;L-Glutamic acid, 4-hydroxy-, (4R)-
CBNumber
CB4706816
Molecular Formula
C5H9NO5
Formula Weight
163.13
MOL File
2485-33-8.mol
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H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Property

Melting point:
>159°C (dec.)
Boiling point:
458.7±45.0 °C(Predicted)
Density 
1.595±0.06 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
pka
2.15±0.10(Predicted)
color 
White to Off-White
optical activity
[α]/D 20.5±1.5°, c = 1 in H2O
BRN 
1725871
Stability:
Hygroscopic
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
76157
Product name
(4R)-4-Hydroxy-L-glutamic acid
Purity
≥98.0% (TLC)
Packaging
10mg
Price
$243
Updated
2024/03/01
Sigma-Aldrich
Product number
76157
Product name
(4R)-4-Hydroxy-L-glutamic acid
Purity
≥98.0% (TLC)
Packaging
50mg
Price
$619
Updated
2024/03/01
TRC
Product number
H942550
Product name
(2S,4R)-4-Hydroxy-L-glutamicAcid
Packaging
10mg
Price
$165
Updated
2021/12/16
Chem-Impex
Product number
07066
Product name
(2,4)-γ-Hydroxy-L-glutamic acid
Purity
≥ 98% (TLC)
Packaging
25MG
Price
$166
Updated
2021/12/16
Chem-Impex
Product number
07066
Product name
(2S,4R)-γ-Hydroxy-L-glutamicacid,≥98%(TLC)
Purity
≥98%(TLC)
Packaging
1G
Price
$1615.58
Updated
2021/12/16
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H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Chemical Properties,Usage,Production

Uses

(2S,4R)-4-Hydroxy-L-glutamic Acid is a metabolite of Glutamic acid (G596960).

Definition

ChEBI: Erythro-4-hydroxy-L-glutamic acid is a 4-hydroxy-L-glutamic acid. It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to a L-glutamic acid. It is a conjugate acid of an erythro-4-hydroxy-L-glutamate(1-).

Biological Activity

(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner. ', 'Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.

H-(2S,4R)-GAMMA-HYDROXY-GLU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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2485-33-8, H-(2S,4R)-GAMMA-HYDROXY-GLU-OHRelated Search:


  • (S)-2-AMINO-[(R)-4],5-DIHYDROXY-OXOPENTANOIC ACID
  • H-(2S,4R)-GAMMA-HYDROXY-GLU-OH
  • H-(2S,4R)-GLU(GAMMA-OH)-OH
  • (2S,4R)-GAMMA-HYDROXY-GLUTAMIC ACID
  • H-(2S,4R)-g-Hydroxy-Glu-OH
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  • (2S,4R)-4-Hydroxy-L-glutaMic Acid
  • (2S,4R)-g-4-Hydroxy-L-glutaMic Acid
  • (4R)-4-Hydroxy-L-glutaMic Acid
  • erythro-4-Hydroxy-L-glutaMic Acid
  • H-(2S,4R)-Glu(g-OH)-OH
  • 4-aMino-3,4-dideoxy-D-erythro-pentaric acid
  • erythro-(4R)-4-Hydroxy-L-glutamic acid
  • H-(2S,4R)-γ-Hydroxy-Glu-OH
  • L-Glutamic acid, 4-hydroxy-, (4R)-
  • (2S,4R)-γ-Hydroxy-L-glutamic acid
  • 2485-33-8