ChemicalBook > CAS DataBase List > 3-Amino-3-(4-fluorophenyl)propanoic acid

3-Amino-3-(4-fluorophenyl)propanoic acid

Uses

Product Name: 3-Amino-3-(4-fluorophenyl)propanoic acid
CAS No.: 325-89-3
Chemical Name: 3-Amino-3-(4-fluorophenyl)propanoic acid
Synonyms: 3-Amino-3-(4-fL;TIMTEC-BB SBB003727;RARECHEM AK HC T330;3-AMINO-(4-FLUOROPHENYL;DL-BETA-(P-FLUOROPHENYL)ALANINE;3-(4-FLUOROPHENYL)-BETA-ALANINE;3-(p-fluorophenyl)-DL-beta-alanine;3-Amino-3-(4-fluorophenyl)propionic;1-(2,5-diethylphenyl)propan-1-amine;3-AMINO-(4-FLUOROPHENYL)PROPIONIC ACID,&
CBNumber: CB4707853
Molecular Formula: C9H10FNO2
Formula Weight: 183.18
MOL File: 325-89-3.mol

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3-Amino-3-(4-fluorophenyl)propanoic acid Property

Melting point:: 224-228 °C (dec.) (lit.)
Boiling point:: 308.8±32.0 °C(Predicted)
Density: 1.289±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 3.66±0.10(Predicted)
color: White to Almost white
optical activity: 0.20°(C=0.55g/100mL, HCL, 20°C, 589nm)
BRN: 3258498
InChIKey: CPGFMWPQXUXQRX-UHFFFAOYSA-N
CAS DataBase Reference: 325-89-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 573418
Product name: 3-Amino-3-(4-fluorophenyl)propionic acid
Purity: 97%
Packaging: 1g
Price: $50.4
Updated: 2023/06/20

TCI Chemical

Product number: A2430
Product name: 3-Amino-3-(4-fluorophenyl)propionic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $239
Updated: 2023/06/20

TRC

Product number: A634645
Product name: 3-Amino-3-(4-fluorophenyl)propanoicAcid
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 008797
Product name: 3-Amino-3-(4-fluorophenyl)propanoic acid
Purity: 97%
Packaging: 1g
Price: $30
Updated: 2021/12/16

Matrix Scientific

Product number: 008797
Product name: 3-Amino-3-(4-fluorophenyl)propanoic acid
Purity: 97%
Packaging: 5g
Price: $90
Updated: 2021/12/16

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3-Amino-3-(4-fluorophenyl)propanoic acid Chemical Properties,Usage,Production

Uses

3-Amino-3-(4-fluorophenyl)propionic acid is a carboxylic acid derivative that can be used as a pharmaceutical intermediate for pharmaceutical synthesis and experimental research.

Chemical Properties

White powder

Synthesis

141-82-2

459-57-4

325-89-3

To a 150 mL round bottom flask was added 30.5 g (0.25 mol) of 4-fluorobenzaldehyde, 25.6 g (0.25 mol) of malonic acid and 28.4 g (0.37 mol) of ammonium acetate dissolved in ethanol. The reaction mixture was heated to 75-80°C and the reaction was stirred under reflux conditions for 8 hours. After completion of the reaction, the mixture was cooled to room temperature and stirring was continued for 1 hour. Subsequently, the precipitate was collected by filtration and dried under reduced pressure at 45°C to give 28.3 g of 3-amino-3-(4-fluorophenyl)propionic acid (racemic mixture) in 62.8% yield (calculated based on 4-fluorobenzaldehyde), the product was a white powder. The physical properties of 3-amino-3-(4-fluorophenyl)propionic acid (racemic mixture) were as follows: 1H-NMR (δ, ppm, D2O): 2.49 (dd, 1H, J = 17.1, 6.8 Hz), 2.62 (dd, 1H, J = 17.1, 7.8 Hz), 4.20 (dd, 1H, J = 7.8, 6.8 Hz), 6.58-6.62 (m, 2H), 6.88-6.91 (m, 1H) 13C-NMR (δ, ppm, D2O): 37.1, 50.5, 115.5, 115.8, 128.9, 130.4, 172.6 MS (EI) m/z: 183 (M+) MS (CI, i-C4H10) m/z: 184 (MH+)

References

[1] Chemical Communications, 2011, vol. 47, # 20, p. 5894 - 5896
[2] Beilstein Journal of Organic Chemistry, 2013, vol. 9, p. 260 - 264
[3] Journal of Medicinal Chemistry, 2001, vol. 44, # 12, p. 1938 - 1950
[4] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 252 - 268
[5] European Journal of Medicinal Chemistry, 1992, vol. 27, # 9, p. 961 - 965

3-Amino-3-(4-fluorophenyl)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-3-(4-fluorophenyl)propanoic acid Suppliers

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View Lastest Price from 3-Amino-3-(4-fluorophenyl)propanoic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 3-Amino-3-(4-fluorophenyl)propionic acid 325-89-3
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 100KG
Release date: 2025-08-20

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Amino-3-(4-fluorophenyl)propanoic acid 325-89-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Amino-3-(4-fluorophenyl)propanoic acid 325-89-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

325-89-3, 3-Amino-3-(4-fluorophenyl)propanoic acidRelated Search:

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DL-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID

DL-BETA-(P-FLUOROPHENYL)ALANINE

RARECHEM AK HC T330

TIMTEC-BB SBB003727

3-AMINO-3-(4-FLUOROPHENYL)PROPANOIC ACID

3-AMINO-3-(4-FLUOROPHENYL)PROPIONIC ACID

3-(4-FLUOROPHENYL)-BETA-ALANINE

3-(p-fluorophenyl)-DL-beta-alanine

3-AMINO-(4-FLUOROPHENYL)PROPIONIC ACID,&

3-AMINO-(4-FLUOROPHENYL

Benzenepropanoic acid, .beta.-amino-4-fluoro-

(RS)-3-Amino-3-(4-fluorophenyl)-propionic acid

3-Amino-3-(4-fluorophenyl)propionic Acid &gt

3-Amino-3-(4-fL

Benzenepropanoic acid, β-amino-4-fluoro-

3-Amino-3-(4-fluorophenyl)propionic

1-(2,5-diethylphenyl)propan-1-amine

325-89-3

C9H10FNO2

FC6H4CHNH2CH2CO2H

Organic Building Blocks

Building Blocks

Carbonyl Compounds

Carboxylic Acids

B-Amino

Carbonyl Compounds

Carboxylic Acids