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MMP-8 INHIBITOR I

Product Name
MMP-8 INHIBITOR I
CAS No.
236403-25-1
Chemical Name
MMP-8 INHIBITOR I
Synonyms
MMP 8-I;MMP-8 INHIBITOR I;MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I);(3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE];3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
CBNumber
CB4710190
Molecular Formula
C17H18N2O5S
Formula Weight
362.4
MOL File
Mol file
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MMP-8 INHIBITOR I Property

storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21852
Product name
MMP-8 Inhibitor I
Purity
≥95%
Packaging
1mg
Price
$201
Updated
2024/03/01
TRC
Product number
M425440
Product name
MMP8-I
Packaging
100mg
Price
$1135
Updated
2021/12/16
AK Scientific
Product number
9999CR
Product name
Mmp-8inhibitori
Packaging
1mg
Price
$322
Updated
2021/12/16
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MMP-8 INHIBITOR I Chemical Properties,Usage,Production

Description

MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.

Uses

MMP 8-I is a matrix metalloproteinase 8 inhibitor. Matrix metalloproteinases are involved with tight junction protein degradation in endothelial cells.

MMP-8 INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP-8 INHIBITOR I Suppliers

China 12 Japan 1 United Kingdom 1 United States 4 Global 18
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
995
Advantage
59
Alabiotech Inc.
Tel
001-619-354-5251
Fax
001-855-855-6087
Email
sales@alabiotech-e.com
Country
United States
ProdList
972
Advantage
60
Alpha Biopharmaceuticals Co., Ltd
Tel
+86-411-39042497 +8613921981412
Fax
0086-411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
886
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19915
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29803
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48467
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
3674309880
Email
hanfangpharma@126.com
Country
China
ProdList
30968
Advantage
58

236403-25-1, MMP-8 INHIBITOR IRelated Search:


  • (3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE]
  • MMP-8 INHIBITOR I
  • MMP 8-I
  • 3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
  • MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I)
  • 236403-25-1