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MMP-8 INHIBITOR I

Product Name
MMP-8 INHIBITOR I
CAS No.
236403-25-1
Chemical Name
MMP-8 INHIBITOR I
Synonyms
MMP 8-I;MMP-8 INHIBITOR I;MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I);(3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE];3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
CBNumber
CB4710190
Molecular Formula
C17H18N2O5S
Formula Weight
362.4
MOL File
Mol file
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MMP-8 INHIBITOR I Property

storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21852
Product name
MMP-8 Inhibitor I
Purity
≥95%
Packaging
1mg
Price
$201
Updated
2024/03/01
TRC
Product number
M425440
Product name
MMP8-I
Packaging
100mg
Price
$1135
Updated
2021/12/16
AK Scientific
Product number
9999CR
Product name
Mmp-8inhibitori
Packaging
1mg
Price
$322
Updated
2021/12/16
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MMP-8 INHIBITOR I Chemical Properties,Usage,Production

Description

MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.

Uses

MMP 8-I is a matrix metalloproteinase 8 inhibitor. Matrix metalloproteinases are involved with tight junction protein degradation in endothelial cells.

MMP-8 INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP-8 INHIBITOR I Suppliers

China 11 Japan 1 United Kingdom 1 United States 4 Global 17
Alabiotech Inc.
Tel
001-619-354-5251
Fax
001-855-855-6087
Email
sales@alabiotech-e.com
Country
United States
ProdList
972
Advantage
60
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

236403-25-1, MMP-8 INHIBITOR IRelated Search:


  • (3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE]
  • MMP-8 INHIBITOR I
  • MMP 8-I
  • 3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
  • MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I)
  • 236403-25-1