ChemicalBook > CAS DataBase List > 2,2,4-Trimethyl-1,3-pentanediol

2,2,4-Trimethyl-1,3-pentanediol

Product Name
2,2,4-Trimethyl-1,3-pentanediol
CAS No.
144-19-4
Chemical Name
2,2,4-Trimethyl-1,3-pentanediol
Synonyms
TMPD GLYCOL;tmpd(alcohol);UNII:WT1X081P0L;Trimethylpentanediol;2,2,4-Trimethylpentandiol;TRIMETHYL-1,3-PENTANEDIOL;1,3-PENTANEDIOL,2,2,4-TRIME;2,2,4-trimethyl-3-pentanediol;2,2,4-TriMethyl-1,3-pentandiol;3-Pentanediol,2,2,4-trimethyl-1
CBNumber
CB4711551
Molecular Formula
C8H18O2
Formula Weight
146.23
MOL File
144-19-4.mol
More
Less

2,2,4-Trimethyl-1,3-pentanediol Property

Melting point:
50-53 °C (lit.)
Boiling point:
232 °C (lit.)
Density 
0,937 g/cm3
vapor pressure 
0.314Pa at 20℃
refractive index 
1.4513
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol
form 
Solid
pka
14.81±0.20(Predicted)
color 
Off-White
Water Solubility 
31.5g/L at 20℃
BRN 
1698098
InChIKey
JCTXKRPTIMZBJT-UHFFFAOYSA-N
LogP
1.25 at 22℃
CAS DataBase Reference
144-19-4(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Pentanediol, 2,2,4-trimethyl-(144-19-4)
EPA Substance Registry System
2,2,4-Trimethyl-1,3-pentanediol (144-19-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
1
RTECS 
SA1400000
TSCA 
Yes
HS Code 
2905.39.9000
Hazardous Substances Data
144-19-4(Hazardous Substances Data)
Toxicity
guinea pig,LD50,oral,2gm/kg (2000mg/kg),Toxicology and Applied Pharmacology. Vol. 29, Pg. 87, 1974.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
327220
Product name
2,2,4-Trimethyl-1,3-pentanediol
Purity
97%
Packaging
1kg
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
T0483
Product name
2,2,4-Trimethyl-1,3-pentanediol
Purity
>97.0%(GC)
Packaging
25g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
T0483
Product name
2,2,4-Trimethyl-1,3-pentanediol
Purity
>97.0%(GC)
Packaging
500g
Price
$151
Updated
2024/03/01
Alfa Aesar
Product number
B21328
Product name
2,2,4-Trimethyl-1,3-pentanediol, 94%
Packaging
10g
Price
$33.6
Updated
2021/12/16
TRC
Product number
T796570
Product name
2,2,4-Trimethyl-1,3-pentanediol
Packaging
50g
Price
$65
Updated
2021/12/16
More
Less

2,2,4-Trimethyl-1,3-pentanediol Chemical Properties,Usage,Production

Chemical Properties

2,2,4-Trimethyl-1,3-pentanediol is a somewhat volatile liquid.

Chemical Properties

(96% pure): White solid. Slightly soluble in water; soluble in alcohol, acetone, ether, and benzene. Combustible.

Uses

Main uses of 2,2,4-Trimethyl-1,3-pentanediol are as a component of polyester resins used in food packaging and as an insect repellent. Industrial exposure is likely to be by direct contact with the liquid. Vapors or mists may be encountered under some conditions.

Uses

2,2,4-Trimethyl-1,3-pentanediol is used in the synthesis of monoisobutyrate derivatives used in film forming auxilleries in paint substances.

Uses

Polyester resins, plasticizers, lubricants, surface coatings and printing inks, insect repellent.

Production Methods

2,2,4-Trimethyl-1,3-pentanediol is made by reacting isobutyryl chloride with ethyl isobutyrate.

Definition

2,2,4-Trimethyl-1,3-pentanediol (TMPD) glycol, with one primary and one secondary hydroxyl function, shows the typical reactivity of a diol. In comparison to other diols, such as 1,4-cyclohexanedimethanol) or NPG (Neopentyl glycol), TMPD glycol has an unsymmetrical structure and shielded hydroxyl groups.    

Flammability and Explosibility

Non flammable

Toxicology

2,2,4-trimethyl-1,3-pentanediol (TMPD Glycol) is classified as "slightly toxic". In rabbits, moderate eye irritation was observed. Slight to no skin irritation occurred in guinea pigs, and no skin sensitization was found. Repeated skin application studies in humans gave no evidence of irritation, sensitization, photosensitization, or systemic toxic effects. In humans, TMPD glycol is rapidly excreted in the urine, partly unchanged, partly as the glucuronide and sulfate conjugates, and partly as 2,2,4-trimethyl-3-hydroxyvaleric acid. LD50 2000 (rat, oral), LD50 145 (rat, intravenous).

2,2,4-Trimethyl-1,3-pentanediol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,2,4-Trimethyl-1,3-pentanediol Suppliers

Belgium 1 Canada 1 China 182 Europe 1 France 1 Germany 7 India 3 Japan 6 Mexico 1 South Korea 1 Sweden 1 Switzerland 2 The Netherlands 2 United Kingdom 10 United States 42 Global 261
Wuhan yuqing jiaheng pharmaceutical co. LTD
Tel
027-83855381 15827508403
Fax
027-83855381
Email
xiaozhan0503@163.com
Country
China
ProdList
1689
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
More
Less

View Lastest Price from 2,2,4-Trimethyl-1,3-pentanediol manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
2,2,4-Trimethyl-1,3-pentanediol 144-19-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Career Henan Chemical Co
Product
2,2,4-Trimethyl-1,3-pentanediol 144-19-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-12-26
Career Henan Chemical Co
Product
2,2,4-Trimethyl-1,3-pentanediol 144-19-4
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-22

144-19-4, 2,2,4-Trimethyl-1,3-pentanediolRelated Search:

2-METHYL-1,3-PROPANEDIOL 1,2-Pentanediol 2,2-Dimethyl-1,3-propanediol 2,2-Bis(bromomethyl)propane-1,3-diol Poly(tetrahydrofuran) Trimethyl borate PICROTOXIN Forskolin DIGOXIN PICROTOXININ 2 2 6 6-TETRAKIS(HYDROXYMETHYL)CYCLOHEX& Limonin 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DIISOBUTYRATE FORSKOLIN, 7-DEACETYL-7-O-HEMISUCCINYL- Nomilin OBACUNON 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate

  • 2,2,4-Trimethylpentandiol
  • 1,3-PENTANEDIOL,2,2,4-TRIME
  • 2,2,4-TRIMETHYLPENTANE-1,3-DIOL 96%
  • 2,2,4-TriMethyl-1,3-pentanediol (TMPD)
  • 2,2,4-Trimethylpentane-1,3-diol,96%
  • 2,2,4-Trimethylpentane-1,3-diol,98%
  • 2,2,4-TriMethyl-1,3-pentandiol
  • UNII:WT1X081P0L
  • 2,2,4-Trimethyl-1,3-pentanediol 97%
  • TMPD GLYCOL
  • 1,3-Dihydroxy-2,2,4-trimethyl pentane
  • 2,2,4-trimethyl-3-pentanediol
  • 3-Pentanediol,2,2,4-trimethyl-1
  • tmpd(alcohol)
  • 2,2,4-TRIMETHYL-1,3-PENTANEDIOL
  • 2，2，4-Trimethyl-1，3-pentylene glycol
  • 2,2,4-TRIMETHYLPENTANE-1,3-DIOL
  • 2,2,4-TRIMETHYL PENTANEDIOL-1,3
  • 2,2,4-TRIMETHYL-1,3-PENTANEDIOL, CRYSTAL LIZED
  • 2,2,4-Trimethyl-1,3-pentanediol, pract.
  • 1,3-Pentanediol, 2,2,4-trimethyl-
  • 2,2,4-Trimethyl-1,3-pentanediol &gt
  • 2,2, 4-trimethyl-1, 3-pentadiol
  • Trimethylpentanediol
  • TRIMETHYL-1,3-PENTANEDIOL
  • 144-19-4
  • CH32CHCHOHCCH32CH2OH
  • Organic Building Blocks
  • Polyols
  • Oxygen Compounds
  • Building Blocks
  • ALCOHOL
  • Alcohols
  • Monomers
  • Polymer Science
  • Fine Chemical