ChemicalBook > CAS DataBase List > L-655,240

L-655,240

Product Name
L-655,240
CAS No.
103253-15-2
Chemical Name
L-655,240
Synonyms
L-655;L-655,240;L 655,240,L655,240;JLPYLHLUHJOPNL-UHFFFAOYSA-N;1-(4-Chlorobenzyl)-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid;1-[(4-Chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid;1-[(4-CHLOROPHENYL)METHYL]-5-FLUORO-A,A,3-TRIMETHYL-1H-INDOLE-2-PROPANOIC ACID;3-[1-(4-CHLOROBENZYL)-5-FLUORO-3-METHYL-INDOL-2-YL]-2,2-DIMETHYL PROPANOIC ACID;1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-;1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoicacid
CBNumber
CB4718318
Molecular Formula
C21H21ClFNO2
Formula Weight
373.85
MOL File
103253-15-2.mol
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L-655,240 Property

Boiling point:
548.7±50.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMSO: 30 mg/mL
form 
solid
pka
4.82±0.10(Predicted)
color 
off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10011562
Product name
L-655,240
Purity
≥98%
Packaging
1mg
Price
$48
Updated
2021/12/16
Cayman Chemical
Product number
10011562
Product name
L-655,240
Purity
≥98%
Packaging
5mg
Price
$216
Updated
2021/12/16
Cayman Chemical
Product number
10011562
Product name
L-655,240
Purity
≥98%
Packaging
10mg
Price
$384
Updated
2021/12/16
Cayman Chemical
Product number
10011562
Product name
L-655,240
Purity
≥98%
Packaging
25mg
Price
$840
Updated
2021/12/16
TRC
Product number
L009505
Product name
L-655,240
Packaging
1mg
Price
$45
Updated
2021/12/16
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L-655,240 Chemical Properties,Usage,Production

Uses

L-655,240 is a selective and potent thromboxane and prostaglandin endoperoxide antagonist. Also used in the structure-based and ligand-based drug design for microsomal prostaglandins E synthase-1 inhibitors.

Definition

ChEBI: 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methyl-2-indolyl]-2,2-dimethylpropanoic acid is a methylindole.

Biological Activity

Potent and selective thromboxane A 2 /prostaglandin endoperoxide receptor antagonist. pA 2 values are 8-8.4 in guinea pig smooth muscle; IC 50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo .

L-655,240 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-655,240 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd
Tel
1701086315
Fax
1701086315@qq.com
Email
dexuanpharma@126.com
Country
China
ProdList
9475
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58

103253-15-2, L-655,240Related Search:


  • L-655,240
  • 1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoicacid
  • 1-(4-Chlorobenzyl)-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid
  • 1-[(4-Chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid
  • 3-[1-(4-CHLOROBENZYL)-5-FLUORO-3-METHYL-INDOL-2-YL]-2,2-DIMETHYL PROPANOIC ACID
  • 1-[(4-CHLOROPHENYL)METHYL]-5-FLUORO-A,A,3-TRIMETHYL-1H-INDOLE-2-PROPANOIC ACID
  • JLPYLHLUHJOPNL-UHFFFAOYSA-N
  • 1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-
  • L-655
  • L 655,240,L655,240
  • 103253-15-2
  • C21H21ClFNO2
  • C21H21O2NClF
  • Prostanoid receptor and related