L-655,240
- Product Name
- L-655,240
- CAS No.
- 103253-15-2
- Chemical Name
- L-655,240
- Synonyms
- L-655;L-655,240;L 655,240,L655,240;JLPYLHLUHJOPNL-UHFFFAOYSA-N;1-(4-Chlorobenzyl)-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid;1-[(4-Chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-1H-indole-2-propanoic acid;1-[(4-CHLOROPHENYL)METHYL]-5-FLUORO-A,A,3-TRIMETHYL-1H-INDOLE-2-PROPANOIC ACID;3-[1-(4-CHLOROBENZYL)-5-FLUORO-3-METHYL-INDOL-2-YL]-2,2-DIMETHYL PROPANOIC ACID;1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-5-fluoro-α,α,3-trimethyl-;1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoicacid
- CBNumber
- CB4718318
- Molecular Formula
- C21H21ClFNO2
- Formula Weight
- 373.85
- MOL File
- 103253-15-2.mol
L-655,240 Property
- Boiling point:
- 548.7±50.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- DMSO: 30 mg/mL
- form
- solid
- pka
- 4.82±0.10(Predicted)
- color
- off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 10011562
- Product name
- L-655,240
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $48
- Updated
- 2021/12/16
- Product number
- 10011562
- Product name
- L-655,240
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $216
- Updated
- 2021/12/16
- Product number
- 10011562
- Product name
- L-655,240
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $384
- Updated
- 2021/12/16
- Product number
- 10011562
- Product name
- L-655,240
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $840
- Updated
- 2021/12/16
- Product number
- L009505
- Product name
- L-655,240
- Packaging
- 1mg
- Price
- $45
- Updated
- 2021/12/16
L-655,240 Chemical Properties,Usage,Production
Uses
L-655,240 is a selective and potent thromboxane and prostaglandin endoperoxide antagonist. Also used in the structure-based and ligand-based drug design for microsomal prostaglandins E synthase-1 inhibitors.
Definition
ChEBI: 3-[1-[(4-chlorophenyl)methyl]-5-fluoro-3-methyl-2-indolyl]-2,2-dimethylpropanoic acid is a methylindole.
Biological Activity
Potent and selective thromboxane A 2 /prostaglandin endoperoxide receptor antagonist. pA 2 values are 8-8.4 in guinea pig smooth muscle; IC 50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo .
L-655,240 Preparation Products And Raw materials
Raw materials
Preparation Products
L-655,240 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77