ChemicalBook > CAS DataBase List > 5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE

5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE

Product Name: 5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE
CAS No.: 107008-28-6
Chemical Name: 5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE
Synonyms: RU-24969;RU 24969 HEMISUCCINATE;5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE;5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hemisuccinate;5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole succinate(2:1);5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole succinate (2:1) salt;Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1)
CBNumber: CB4720764
Molecular Formula: C18H22N2O5
Formula Weight: 346.38
MOL File: 107008-28-6.mol

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5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE Property

storage temp.: Inert atmosphere,Room Temperature
form: Solid
color: Light yellow to yellow
InChI: InChI=1S/2C14H16N2O.C4H6O4/c2*1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10;5-3(6)1-2-4(7)8/h2*2-4,8-9,15-16H,5-7H2,1H3;1-2H2,(H,5,6)(H,7,8)
InChIKey: BNYJLRQAWCQJOM-UHFFFAOYSA-N
SMILES: N1C2C=CC(OC)=CC=2C(C2CCNCC=2)=C1.C(O)(=O)CCC(O)=O.N1C2C=CC(OC)=CC=2C(C2CCNCC=2)=C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0912
Product name: RU24969hemisuccinate
Purity: ≥99%(HPLC)
Packaging: 10
Price: $161
Updated: 2021/12/16

Tocris

Product number: 0912
Product name: RU24969hemisuccinate
Purity: ≥99%(HPLC)
Packaging: 50
Price: $664
Updated: 2021/12/16

TRC

Product number: R701778
Product name: RU24969Succinate
Packaging: 10mg
Price: $115
Updated: 2021/12/16

Usbiological

Product number: 256531
Product name: RU 24969 hemisuccinate
Packaging: 10mg
Price: $403
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611719
Product name: RU-24969
Packaging: 50mg
Price: $493
Updated: 2021/12/16

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5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE Chemical Properties,Usage,Production

Uses

RU 24969 Succinate is a SR-1A and SR-1B, and moderate SR-2C agonist. 5-HT1B/1A agonist. Also, it is a well-established substrate for human serotonin transporter (SERT).

Biological Activity

Potent 5-HT 1A/1B and moderate 5-HT 2C agonist that may also release 5-HT. Centrally active following systemic administration.

in vivo

RU 24969 succinate (1 and 3 mg/kg; s.c., once) potentiates addictive agent-induced effects^[2]. RU 24969 succinate (0.03-3.0 mg/kg; s.c., once) dose-dependently decreases water consumption in water deprived rats^[4].

Animal Model:	Male Wistar rats with cocaine injection^[2]
Dosage:	1 and 3 mg/kg
Administration:	Subcutaneous injection; 1 and 3 mg/kg, once
Result:	Increased cocaine-induced elevation of nucleus accumbens (NAcc) dopamine DA levels and reduction of ventral tegmental area (VTA) GABA levels.

5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE Suppliers

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107008-28-6, 5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATERelated Search:

5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE

RU 24969 HEMISUCCINATE

5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole succinate (2:1) salt

RU-24969

Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1)

5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hemisuccinate

5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole succinate(2:1)

107008-28-6

C14H16N2O189C4H6O4

Inhibitors

Serotonin receptor