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(1R,2R)-(+)-1,2-Diphenylethylenediamine

Product Name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
CAS No.
35132-20-8
Chemical Name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
Synonyms
(1R,2R)-1,2-diphenylethane-1,2-diamine;(1R,2R)-1,2-DIPHENYLETHYLENEDIAMINE;R-DPEN;(1R,2R)-1,2-DIPHENYL-1,2-ETHANEDIAMINE;(1R,2R)-(+)-1,2-Diph;(1R,2R)-(+)-1,2-DiphenyL;(1R,2R)-1,2-Diphenyldiamine;(αS,βS)-Bibenzyl-α,β-diamine;(1S,2S)-(+)-1,2-Diphenylethane;(+)-1,2-Diphenylethylenediamine
CBNumber
CB4727536
Molecular Formula
C14H16N2
Formula Weight
212.29
MOL File
35132-20-8.mol
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(1R,2R)-(+)-1,2-Diphenylethylenediamine Property

Melting point:
79-83 °C(lit.)
alpha 
104 º (c=1.1, MeOH 25 ºC)
Boiling point:
342.14°C (rough estimate)
Density 
1.0799 (rough estimate)
refractive index 
103 ° (C=1, EtOH)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
9.78±0.10(Predicted)
color 
White to light yellow
optical activity
[α]20/D +102°, c = 1 in ethanol
Water Solubility 
Insoluble in water.
Sensitive 
Air Sensitive
BRN 
2369988
Stability:
Hygroscopic
InChI
1S/C14H16N2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14H,15-16H2/t13-,14-/m1/s1
InChIKey
PONXTPCRRASWKW-ZIAGYGMSSA-N
SMILES
N[C@@H]([C@H](N)c1ccccc1)c2ccccc2
CAS DataBase Reference
35132-20-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
10-23
HazardClass 
8
HS Code 
29212900
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
364010
Product name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
Purity
97%
Packaging
500mg
Price
$70.8
Updated
2026/03/19
Sigma-Aldrich
Product number
364010
Product name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
Purity
97%
Packaging
1g
Price
$119
Updated
2026/03/19
TCI Chemical
Product number
D2176
Product name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$32
Updated
2026/03/19
TCI Chemical
Product number
D2176
Product name
(1R,2R)-(+)-1,2-Diphenylethylenediamine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$122
Updated
2026/03/19
Strem Chemicals
Product number
07-0474
Product name
(1R,2R)-(+)-1,2-Diphenylethylenediamine, min. 97% (R,R)-DPEN
Packaging
500mg
Price
$52
Updated
2024/03/01
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(1R,2R)-(+)-1,2-Diphenylethylenediamine Chemical Properties,Usage,Production

Description

(1R,2R)-(+)-1,2-Diphenylethylenediamine is a chiral reagent widely used in the chemical industry at present, used for asymmetric synthesis and optical resolution.

Chemical Properties

white to light yellow crystal powder

Uses

(1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine is used as chiral solvation agent for determination of enantiomeric excess of chiral acids by NMR. It is used in various catalyst systems for asymmetric reactions.

Synthesis

Add 1,2-diphenylethanedione dioxime (48g, 0.20mol) and 260ml methanol in a 500ml four-necked flask equipped with a condenser, stir to dissolve all of them, and then add 2g of activated charcoal (120 mesh), 0.5g of Raney's nickel, raise the temperature to 60 , and then add 80% hydrazine hydrate (28.75g, 0.46mol) slowly dropwise, and keep the temperature of the reaction between 58 -62 , there is nitrogen emission during the reaction, and the rate of dropwise acceleration is controlled to keep the nitrogen emission rate not too fast, and liquid chromatography tracks the reaction process. -62 , the reaction process has nitrogen release, drop acceleration control in the nitrogen release rate is not too fast as well, liquid chromatography to track the reaction process, when the raw material 1,2-diphenylethanedione dioxime disappeared after the end of the reaction, cooling the mixture, filtration of Ranieri nickel and activated carbon, to a small amount of water covered with a preserved in order to prepare for sets of use, the filtrate distillation to recover the methanol, and the residue added to 200 ml of petroleum ether heated to make all dissolved, cooled for 24 hours and filtered to get the product The residue was heated by adding 200 ml of petroleum ether to dissolve all of it, then cooled and filtered for 24 hours to obtain the product (1R,2R)-1,2-diphenylethylenediamine 41.55g, yield 98%, chemical purity 99.57%.

(1R,2R)-(+)-1,2-Diphenylethylenediamine Preparation Products And Raw materials

Raw materials

Sodium acetate Ethanol Acetic anhydride N,N-Dimethylformamide D-(-)-Tartaric Acid Sodium Sodium ethoxide Hydrogen bromide Benzaldehyde Hydrochloric acid Acetic acid Cyclohexanone Benzil Lithium Ammonia

Preparation Products

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(1R,2R)-(+)-1,2-Diphenylethylenediamine Suppliers

Americas 1 Belgium 3 Canada 1 China 307 Europe 3 France 1 Germany 7 India 9 Ireland 1 Italy 2 Japan 6 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 21 United States 59 Global 426
Shaoxing Zejun Pharmaceuticals Co.,Ltd
Tel
0575-82126188 13858337171
Email
service@zejunpharma.com
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China
ProdList
478
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Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
4015
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50
Chengdu rongchuangyiheng Biomedical Technology Co., Ltd
Tel
13438025684
Email
28296972@qq.com
Country
China
ProdList
146
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58
ZhengZhou Edward Biology Co.,Ltd
Tel
13298105281
Email
1522334715@qq.com
Country
China
ProdList
7507
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58
Chengdu Likai Chiral Tech LTD.
Tel
028-85247892 18980630336;
Email
suriya@lkchiralchina.com
Country
China
ProdList
45
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
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57
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
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66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from (1R,2R)-(+)-1,2-Diphenylethylenediamine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
(1R,2R)-(+)-1,2-Diphenylethylenediamine 35132-20-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30
Henan Aochuang Chemical Co.,Ltd.
Product
(1R,2R)-(+)-1,2-Diphenylethylenediamine 35132-20-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Shanghai UCHEM Inc.
Product
(1R,2R)-(+)-1,2-Diphenylethylenediamine 35132-20-8
Price
US $11.00-193.00/g
Min. Order
1g
Purity
0.98
Supply Ability
25kg
Release date
2023-10-13

35132-20-8, (1R,2R)-(+)-1,2-DiphenylethylenediamineRelated Search:

1,3-Diaminoguanidine monohydrochloride N,N,N',N'-Tetramethylethylenediamine 1,2-Diphenylethane 2-Aminoethylammonium chloride Biphenyl N-(1-Naphthyl)ethylenediamine dihydrochloride Lysergic acid diethylamide 1,2-Diphenylethylenediamine,Racemic 1,2-Diphenylethylenediamine (1R,2R)-(-)-N-p-Tosyl-1,2-diphenylethylenediamine Ethylenediamine (1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+% (1S,2S)-(-)-1,2-Diphenylethylenediamine-C14H16N2,(1S,2S)-(-)-1,2-Diphenylethylenediamine,min.97%(S,S)-DPEN,(1S,2S)-(-)-1,2-DIPHENYLETHYLENEDIAMINE (S,S)-DPEN 2,2-Diphenylethylamine (R,R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine(Chloro)(p-cymene)ruthenium(II) Dichloro[(R)-(-)-4,12-bis(di(3,5-xylyl)phosphino)-[2.2]-paracyclophane][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) 1,2-Dianilinoethane (1S,2S)-(+)-N-(4-Toluenesulfonyl)-1,2-diphenylethylenediamine DICHLORO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL][(1S,2S)-(-)-1,2-DIPHENYLETHYLENEDIAMINE]RUTHENIUM (II)

  • (R,R)-(+)-1,2-DIPHENYLETHYLENEDIAMINE
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine ee
  • (1S,2S)-1,2-Diphenyl-1,2-diaminoethane
  • (αS,βS)-Bibenzyl-α,β-diamine
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine ,98% [99%,e.e.]
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine ,99% [ee:99%]
  • (1R,2R)-Diphenyl-1,2-ethanediamine
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine, 98+%, ee 98%
  • (1R,2R)-(+)-1,2-Diph
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine,99%,99% ee
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediaMine, 99% ee, 99% 250MG
  • ((1R,2R)-2-AMino-1,2-diphenylethyl)aMine
  • (R,R)-1,2-DiaMino-1,2-diphenylethane
  • (R,R)-1,2-Diphenylethylene-1,2-diaMine
  • (1R,2R)-(+)-1,2-DiphenylethylenediaMine,(R,R)-DPEN
  • (1R,2R)-(+)-1,2-DiphenylethylenediaMine, ee: 99%
  • (1R,2R)-(+)-1,2-diphenylethylendediamine
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine, 98+%
  • (1R,2R)-1,2-Diphenylethane-1,2-diamine 98%
  • (1R,2R)-DIPHENYL-ETHANE-1,2-DIAMINE
  • (1R,2R)-(+)-1,2-DIAMINO-1,2-DIPHENYLETHANE
  • (1R,2R)-(+)-1,2-DIPHENYL-1,2-ETHANEDIAMINE
  • (1R,2R)-1,2-DIPHENYL-1,2-ETHANEDIAMINE
  • (1R,2R)-(+)-1,2-DIPHENYL-1,2-ETHYLENEDIAMINE
  • (1R,2R)-(-)-1,2-DIPHENYLETHYLENEDIAMINE
  • (1R,2R)-(+)-1,2-DIPHENYLETHYLENEDIAMINE
  • 1,2-ETHANEDIAMINE, 1,2-DIPHENYL-, (1R,2R)-
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine, 99% ee, 99%
  • (1S,2S)-(+)-1,2-Diphenylethane
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine,min.97%(R,R)-DPEN
  • (1S,2S)-(-)-1,2-Diphenylenediamine
  • (1R,2R)-(+)-1,2-DIPHENYLETHYLENDIAMIN
  • (1R,2R)-(+)-1,2-DIPHENYLETHYLENEDIAMINE, 97% (99% EE/GLC)
  • (1R,2R)-(+)-1,2-DiphenylethylenediaMine, 97+%
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine,97% (R,R)-DPEN
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine (1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine
  • (<i>1R,2R</i>)-(+)-1,2-Diphenylethylenediamine
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine 97%
  • (R,R)-DPEN , (1R,2R)-1,2-Diphenyl-1,2-ethanediamine, 98%
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine≥ 99.5% (HPLC, Chiral purity)
  • (1R,2R)-Diphenylethane-1,2-diamine,99%e.e.
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine, min. 97%
  • (1R,2R)-(+)-1,2-Diphenyl-1,2-diaminoethane
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine, 99%, ee: 99%
  • (1R,2R)-(+)-1,2-DIPHENYL-1,2-ETHANEDIAMI
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine&gt
  • (1R,2R)-(+)-1,2-DiphenyL
  • (1R,2R)-(+)-1,2-Diphenylethylenediamine,min.97%
  • (+)-1,2-Diphenylethylenediamine
  • (1R,2R)-1,2-Diphenylethylenediamine / R-DPEN
  • (1<i>R</i>,2<i>R</i>)-(+)-1,2-Diphenylethylenediamine
  • (1R,2R)-1,2-Diphenyldiamine
  • (1R,2R)-(+)-1,2-diphenylethyldiamine
  • R-DPEN
  • (1R,2R)-1,2-DIPHENYLETHYLENEDIAMINE
  • (1R,2R)-1,2-diphenylethane-1,2-diamine
  • 35132-20-8
  • C6H5NH2CHCHNH2C6H5