S-1 METHANANDAMIDE
- Product Name
- S-1 METHANANDAMIDE
- CAS No.
- 157182-50-8
- Chemical Name
- S-1 METHANANDAMIDE
- Synonyms
- S-1 METHANANDAMIDE;S(-)-METHANANDAMIDE;S-1 Methanandamide Exclusive;S(-)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE;(S)-(-)-ARACHIDONOYL-1'-HYDROXY-2'-PROPYLAMIDE;N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-[(2S)-1-hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide;5,8,11,14-Eicosatetraenamide, N-[(1S)-2-hydroxy-1-methylethyl]-, (5Z,8Z,11Z,14Z)-
- CBNumber
- CB4740139
- Molecular Formula
- C23H39NO2
- Formula Weight
- 361.56
- MOL File
- Mol file
S-1 METHANANDAMIDE Property
- Boiling point:
- 529.0±50.0 °C(Predicted)
- Density
- 0.935±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO;dimethyl formamide;acetonitril
- form
- solution in ethanol.
- pka
- 14.51±0.10(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 90072
- Product name
- S-1 Methanandamide
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $53
- Updated
- 2024/03/01
- Product number
- 90072
- Product name
- S-1 Methanandamide
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $96
- Updated
- 2024/03/01
- Product number
- 90072
- Product name
- S-1 Methanandamide
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $214
- Updated
- 2024/03/01
- Product number
- C5509
- Product name
- S-1Methanandamide
- Packaging
- 10mg(solution)
- Price
- $108
- Updated
- 2021/12/16
- Product number
- CHM1015119
- Product name
- N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.92
- Updated
- 2021/12/16
S-1 METHANANDAMIDE Chemical Properties,Usage,Production
Definition
ChEBI: S-1 methanandamide is a carboximidic acid.
Biological Activity
s-1 methanandamide is a cb1 receptor ligand.the cannabinoid receptor type 1 (cb1), is a g protein-coupled cannabinoid receptor located mainly in the central and peripheral nervous system. cb1 is also expressed in several cells relating to metabolism, such as muscle cells, fat cells, liver cells, and the digestive tract. the cb1 receptor has been involved in the maintenance of homeostasis in health and disease, preventing the development of excessive neuronal activity, reducing pain and other inflammatory symptoms. enhanced receptor expression has been identified in human hepatocellular carcinoma tumor samples and human prostate cancer cells [2].s-1 methanandamide was a less potent than the c-1 (r) methyl isomer when binding with cb1 receptor. s-1 methanandamide inhibited electrically evoked contractions in isolated mouse vasa deferentia with an ic50 value of 230 nm. the binding affinity of s-1 methanandamide for cb1 receptors was less than that of aea, with a ki of 175 nm for the displacement of radiolabeled cp 55,940 [1].
References
[1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] howlett a c. cannabinoid receptor signaling[m]//cannabinoids. springer berlin heidelberg, 2005: 53-79.
S-1 METHANANDAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
S-1 METHANANDAMIDE Suppliers
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