2-(4-Chlorobenzyl)benzimidazole

Product Name: 2-(4-Chlorobenzyl)benzimidazole
CAS No.: 5468-66-6
Chemical Name: 2-(4-Chlorobenzyl)benzimidazole
Synonyms: ZERENEX E/5046116;2-(4-Chlorobenzyl)be;p-Chlorobenzyl Benzimidazole;2-(P-CHLOROBENZYL)BENZIMIDAZOL;2-(4-CHLOROBENZYL)BENZIMIDAZOLE;2-(P-CHLOROBENZYL)BENZIMIDAZOLE;2-of chloridebenzyl benziMidazole;2-on chloridebenzyl benziMidazole;Chlorobenzyl benziMidazole (CBBI);2-(p-Chlorobenzyl)benzimidazole,99%
CBNumber: CB4754761
Molecular Formula: C14H11ClN2
Formula Weight: 242.7
MOL File: 5468-66-6.mol

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2-(4-Chlorobenzyl)benzimidazole Property

Melting point:: 197.3-198 °C
Boiling point:: 479.7±28.0 °C(Predicted)
Density: 1.301±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.72±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C14H11ClN2/c15-11-7-5-10(6-8-11)9-14-16-12-3-1-2-4-13(12)17-14/h1-8H,9H2,(H,16,17)
InChIKey: COGUOPIIFAMLES-UHFFFAOYSA-N
SMILES: C1(CC2=CC=C(Cl)C=C2)NC2=CC=CC=C2N=1
CAS DataBase Reference: 5468-66-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-36
Safety Statements: 37/39-26-36
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C429083
Product name: 2-(4-Chlorobenzyl)benzimidazole
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC126433
Product name: 2-(4-Chlorobenzyl)-1H-benzimidazole
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 066569
Product name: 2-(4-Chlorobenzyl)-1H-benzimidazole
Packaging: 500mg
Price: $95
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC126433
Product name: 2-(4-Chlorobenzyl)-1H-benzimidazole
Packaging: 1g
Price: $105
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC126433
Product name: 2-(4-Chlorobenzyl)-1H-benzimidazole
Packaging: 2g
Price: $179
Updated: 2021/12/16

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2-(4-Chlorobenzyl)benzimidazole Chemical Properties,Usage,Production

Chemical Properties

purple-pinkish crystalline powder

Synthesis

1878-66-6

95-54-5

5468-66-6

The general procedure for the synthesis of 2-(4-chlorobenzyl)benzimidazole from 4-chlorophenylacetic acid and o-phenylenediamine was as follows: 4-chlorophenylacetic acid (101.8 mmol) and sodium benzoate (0.37 mg, 0.46 mmol) were added to a 50 mL reaction flask fitted with a mechanical stirrer, a thermometer, a water separator and a reflux condenser. The reaction mixture was heated to 110 °C, followed by the addition of o-phenylenediamine (10 g, 92.5 mmol) and the temperature was raised to 120 °C and maintained for 1 hour. The course and endpoint of the reaction was monitored by thin layer chromatography (TLC) (unfolding agent: ethyl acetate to petroleum ether in a volume ratio of 1:1, Rf=0.41). Upon completion of the reaction, the reaction mixture was neutralized with 5% by weight NaOH solution to pH 7.0 to 8.5. The resulting precipitate was filtered and washed with water to neutrality to give the crude product. The crude product was recrystallized with a mixed ethanol-water solvent (1:2 to 1:3, v/v), filtered and dried to give 21.3 g of pure 2-(4-chlorobenzyl)benzimidazole.

References

[1] Patent: CN103483266, 2016, B. Location in patent: Paragraph 0054; 0055; 0056
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 8, p. 1872 - 1878
[3] Journal of the American Chemical Society, 1954, vol. 76, p. 1883,1886
[4] Pharmazie, 2003, vol. 58, # 5, p. 303 - 307

2-(4-Chlorobenzyl)benzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-Chlorobenzyl)benzimidazole Suppliers

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View Lastest Price from 2-(4-Chlorobenzyl)benzimidazole manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2-(4-Chlorobenzyl)benzimidazole 5468-66-6
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-25

Shanghai UCHEM Inc.

Product: 2-(4-Chlorobenzyl)benzimidazole 5468-66-6
Price: US $19.00-166.00/g
Min. Order: 100g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-(4-Chlorobenzyl)benzimidazole 5468-66-6
Price: US $30.00-10.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 100000kg
Release date: 2024-08-19

5468-66-6, 2-(4-Chlorobenzyl)benzimidazoleRelated Search:

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ZERENEX E/5046116

2-(p-Chlorobenzyl)benzimidazole,99%

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2-on chloridebenzyl benziMidazole

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Chlorobenzyl benziMidazole (CBBI)

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1(H)-2-(P-CHLORO)-BENZYL BENZIMIDAZ

1H-Benzimidazole 2-[(4-chlorophenyl)methyl]

p-Chlorobenzyl Benzimidazole

2-(4-chlorobenzyl)benzimidazole 99%

2-[(4-Chlorophenyl)methyl]-1H-benzo[d]imidazole

5468-66-6

5468-66-0

6568-66-6

2835-68-7

C14H11N2C

C14H11ClN2

Imidazol&Benzimidazole

Electronic Chemicals