ChemicalBook > CAS DataBase List > 2-Methylbenzimidazole

2-Methylbenzimidazole

Product Name
2-Methylbenzimidazole
CAS No.
615-15-6
Chemical Name
2-Methylbenzimidazole
Synonyms
2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
CBNumber
CB5439553
Molecular Formula
C8H8N2
Formula Weight
132.16
MOL File
615-15-6.mol
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2-Methylbenzimidazole Property

Melting point:
175-177 °C (lit.)
Boiling point:
234.08°C (rough estimate)
Density 
1.1083 (rough estimate)
refractive index 
1.6013 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
6.19(at 25℃)
color 
Light beige to brown
Water Solubility 
slightly soluble
BRN 
112264
InChIKey
LDZYRENCLPUXAX-UHFFFAOYSA-N
CAS DataBase Reference
615-15-6(CAS DataBase Reference)
NIST Chemistry Reference
1H-benzimidazole, 2-methyl-(615-15-6)
EPA Substance Registry System
1H-Benzimidazole, 2-methyl- (615-15-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41-20/21/22
Safety Statements 
26-39-45-44
WGK Germany 
3
RTECS 
DD9100000
TSCA 
Yes
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M29800
Product name
2-Methylbenzimidazole
Purity
98%
Packaging
5g
Price
$36.4
Updated
2024/03/01
Sigma-Aldrich
Product number
M29800
Product name
2-Methylbenzimidazole
Purity
98%
Packaging
100g
Price
$133
Updated
2024/03/01
TCI Chemical
Product number
M0286
Product name
2-Methylbenzimidazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
M0286
Product name
2-Methylbenzimidazole
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$144
Updated
2024/03/01
Alfa Aesar
Product number
A17290
Product name
2-Methylbenzimidazole, 98%
Packaging
50g
Price
$35.65
Updated
2024/03/01
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2-Methylbenzimidazole Chemical Properties,Usage,Production

Chemical Properties

light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.

Uses

  • 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
  • It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
  • It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
  • 2-Methylbenzimidazole also exhibits corrosion inhibition.

Definition

ChEBI: 2-Methyl-1H-benzo[d]imidazole is a member of benzimidazoles.

Preparation

2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447
Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

2-Methylbenzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methylbenzimidazole Suppliers

Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10057
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 2-Methylbenzimidazole manufacturers

airuikechemical co., ltd.
Product
2-Methylbenzimidazole 615-15-6
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Hebei Weibang Biotechnology Co., Ltd
Product
2-Methylbenzimidazole 615-15-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-09
Shaanxi Dideu Medichem Co. Ltd
Product
2-Methylbenzimidazole 615-15-6
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
2000tons
Release date
2019-12-31

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