2-Methylbenzimidazole

Product Name: 2-Methylbenzimidazole
CAS No.: 615-15-6
Chemical Name: 2-Methylbenzimidazole
Synonyms: 2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
CBNumber: CB5439553
Molecular Formula: C8H8N2
Formula Weight: 132.16
MOL File: 615-15-6.mol

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2-Methylbenzimidazole Property

Melting point:: 175-177 °C (lit.)
Boiling point:: 234.08°C (rough estimate)
Density: 1.1083 (rough estimate)
refractive index: 1.6013 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Crystalline Powder
pka: 6.19(at 25℃)
color: Light beige to brown
Water Solubility: slightly soluble
BRN: 112264
InChIKey: LDZYRENCLPUXAX-UHFFFAOYSA-N
CAS DataBase Reference: 615-15-6(CAS DataBase Reference)
NIST Chemistry Reference: 1H-benzimidazole, 2-methyl-(615-15-6)
EPA Substance Registry System: 1H-Benzimidazole, 2-methyl- (615-15-6)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41-20/21/22
Safety Statements: 26-39-45-44
WGK Germany: 3
RTECS: DD9100000
TSCA: Yes
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M29800
Product name: 2-Methylbenzimidazole
Purity: 98%
Packaging: 5g
Price: $36.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: M29800
Product name: 2-Methylbenzimidazole
Purity: 98%
Packaging: 100g
Price: $133
Updated: 2024/03/01

TCI Chemical

Product number: M0286
Product name: 2-Methylbenzimidazole
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $26
Updated: 2024/03/01

TCI Chemical

Product number: M0286
Product name: 2-Methylbenzimidazole
Purity: >98.0%(GC)(T)
Packaging: 250g
Price: $144
Updated: 2024/03/01

Alfa Aesar

Product number: A17290
Product name: 2-Methylbenzimidazole, 98%
Packaging: 50g
Price: $35.65
Updated: 2024/03/01

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2-Methylbenzimidazole Chemical Properties,Usage,Production

Chemical Properties

light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.

Uses

2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
2-Methylbenzimidazole also exhibits corrosion inhibition.

Definition

ChEBI: 2-Methyl-1H-benzo[d]imidazole is a member of benzimidazoles.

Preparation

2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447
Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

2-Methylbenzimidazole Preparation Products And Raw materials

Raw materials

o-Phenylenediamine

Preparation Products

Vitamin B12

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2-Methylbenzimidazole Suppliers

Americas 1 Belgium 2 China 288 Europe 4 Germany 6 India 22 Japan 6 Russia 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 United Kingdom 15 United States 34 Global 385

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

CHEMSTEP

Tel: --
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Email: info@chemstep.com
Country: Europe
ProdList: 6143
Advantage: 51

ecochem international chemical broker

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Email: export@ecochem.dk
Country: Europe
ProdList: 6371
Advantage: 66

kemikalieimport

Tel: --
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Email: Sales@kemikalieimport.dk
Country: Europe
ProdList: 6685
Advantage: 47

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View Lastest Price from 2-Methylbenzimidazole manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Methylbenzimidazole 615-15-6
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

airuikechemical co., ltd.

Product: 2-Methylbenzimidazole 615-15-6
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Methylbenzimidazole 615-15-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2022-10-10

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