2-Methylbenzimidazole
- Product Name
- 2-Methylbenzimidazole
- CAS No.
- 615-15-6
- Chemical Name
- 2-Methylbenzimidazole
- Synonyms
- 2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
- CBNumber
- CB5439553
- Molecular Formula
- C8H8N2
- Formula Weight
- 132.16
- MOL File
- 615-15-6.mol
2-Methylbenzimidazole Property
- Melting point:
- 175-177 °C (lit.)
- Boiling point:
- 234.08°C (rough estimate)
- Density
- 1.1083 (rough estimate)
- refractive index
- 1.6013 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 6.19(at 25℃)
- color
- Light beige to brown
- Water Solubility
- slightly soluble
- BRN
- 112264
- InChIKey
- LDZYRENCLPUXAX-UHFFFAOYSA-N
- CAS DataBase Reference
- 615-15-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 1H-benzimidazole, 2-methyl-(615-15-6)
- EPA Substance Registry System
- 1H-Benzimidazole, 2-methyl- (615-15-6)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41-20/21/22
- Safety Statements
- 26-39-45-44
- WGK Germany
- 3
- RTECS
- DD9100000
- TSCA
- Yes
- HS Code
- 29339990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- M29800
- Product name
- 2-Methylbenzimidazole
- Purity
- 98%
- Packaging
- 5g
- Price
- $36.4
- Updated
- 2024/03/01
- Product number
- M29800
- Product name
- 2-Methylbenzimidazole
- Purity
- 98%
- Packaging
- 100g
- Price
- $133
- Updated
- 2024/03/01
- Product number
- M0286
- Product name
- 2-Methylbenzimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $26
- Updated
- 2024/03/01
- Product number
- M0286
- Product name
- 2-Methylbenzimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 250g
- Price
- $144
- Updated
- 2024/03/01
- Product number
- A17290
- Product name
- 2-Methylbenzimidazole, 98%
- Packaging
- 50g
- Price
- $35.65
- Updated
- 2024/03/01
2-Methylbenzimidazole Chemical Properties,Usage,Production
Chemical Properties
light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.
Uses
- 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
- It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
- It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
- 2-Methylbenzimidazole also exhibits corrosion inhibition.
Definition
ChEBI: 2-Methyl-1H-benzo[d]imidazole is a member of benzimidazoles.
Preparation
2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447
Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
2-Methylbenzimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methylbenzimidazole Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 2-Methylbenzimidazole manufacturers
- Product
- 2-Methylbenzimidazole 615-15-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-31
- Product
- 2-Methylbenzimidazole 615-15-6
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-08
- Product
- 2-Methylbenzimidazole 615-15-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2022-10-10