ChemicalBook > CAS DataBase List > 2,4-DICHLOROQUINOLINE

2,4-DICHLOROQUINOLINE

Product Name
2,4-DICHLOROQUINOLINE
CAS No.
703-61-7
Chemical Name
2,4-DICHLOROQUINOLINE
Synonyms
AURORA KA-3862;IFLAB-BB F1706-0118;2,4-DICHLOROQUINOLINE;Quinoline,2,4-dichloro-;2,4-Dichloroquinoline>2,4-Dichloroquinoline 98%;2-4-Dichloro-1-azanaphthalene;2,4-dichloroquinoline(SALTDATA: FREE)
CBNumber
CB4757939
Molecular Formula
C9H5Cl2N
Formula Weight
198.05
MOL File
703-61-7.mol
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2,4-DICHLOROQUINOLINE Property

Melting point:
52-54
Boiling point:
282°C(lit.)
Density 
1.4178 (rough estimate)
refractive index 
1.6610 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Methanol
form 
Solid
pka
-1.10±0.50(Predicted)
color 
White
λmax
305nm(MeOH)(lit.)
InChIKey
QNBJYUUUYZVIJP-UHFFFAOYSA-N
CAS DataBase Reference
703-61-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-41-37/38-25
Safety Statements 
26-36-45-39
RIDADR 
2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
2933491090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4452
Product name
2,4-Dichloroquinoline
Purity
>98.0%(GC)
Packaging
5g
Price
$82
Updated
2024/03/01
TCI Chemical
Product number
D4452
Product name
2,4-Dichloroquinoline
Purity
>98.0%(GC)
Packaging
25g
Price
$244
Updated
2024/03/01
TRC
Product number
D436225
Product name
2,4-Dichloroquinoline
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD42902
Product name
2,4-Dichloroquinoline
Packaging
1g
Price
$50
Updated
2021/12/16
Apolloscientific
Product number
OR3822
Product name
2,4-Dichloroquinoline
Purity
98%
Packaging
1g
Price
$22
Updated
2021/12/16
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2,4-DICHLOROQUINOLINE Chemical Properties,Usage,Production

Uses

2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.

Synthesis

The synthesis of 2,4-dichloroquinoline is as follows:A suspension of quinoline-2,4-diol (150 g, 931 mmol) in POCl3 (975 mL, 10.4 mol) was stirred at reflux for 6 hr and the reaction mixture was concentrated. The residue was diluted with CHCl3 (500 mL) and the solution was poured into ice water. The aqueous layer was extracted with CHCl3 (three times). The combined organic layer was dried over MgSO4, filtrated, concentrated, and purified by flash chromatography (silica gel, 20% EtOAc in hexane) to give 2,4-dichloroquinoline (177 g, 96%) as a pale brown solid.  

2,4-DICHLOROQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4-DICHLOROQUINOLINE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2,4-DICHLOROQUINOLINE 703-61-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Career Henan Chemical Co
Product
2,4-DICHLOROQUINOLINE 703-61-7
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-20

703-61-7, 2,4-DICHLOROQUINOLINERelated Search:

2,4-DICHLOROQUINOLINE 2,4-DICHLORO-6-METHYLQUINOLINE 4,8-DICHLOROQUINOLINE Methyl 4,8-dichloroquinoline-2-carboxylate 2,3-DICHLOROQUINOLINE 2,8-DICHLOROQUINOLINE 4,6-Dichloroquinoline 98%,4,6-DICHLOROQUINOLINE 6,7-Dichloroquinoline 4-HYDROXY-6,8-DICHLOROQUINOLINE 4,7-DICHLOROQUINOLINE, 99+%,4,7-Dichloroquinoline,97%,4,7-DICHLOROQUINOLINE,4,7-DICHLOROQUINOLINE CHLOROQUINE PHOSPHATE ETHYL 4,6-DICHLOROQUINOLINE-3-CARBOXYLATE 2,6-DICHLOROQUINOLINE 6,8-Dichloroquinoline 3,7-DICHLOROQUINOLINE-8-CARBOXYLIC ACID,3，7-Dichloroquinoline acid-8 2,6-Dichloroquinoline-3-carboxaldehyde 2,4-DICHLORO-6-METHOXYQUINOLINE 2,4-Dichloroquinoline-3-carboxaldehyde 2,4-DICHLORO-3-METHYLQUINOLINE

  • 2,4-DICHLOROQUINOLINE
  • AURORA KA-3862
  • IFLAB-BB F1706-0118
  • 2,4-Dichloroquinoline 98%
  • 2,4-dichloroquinoline(SALTDATA: FREE)
  • 2-4-Dichloro-1-azanaphthalene
  • Quinoline,2,4-dichloro-
  • 2,4-Dichloroquinoline&gt
  • 703-61-7
  • C9H5CI2N
  • pharmacetical