4-CHLOROFURO[3,2-C]PYRIDINE

Product Name: 4-CHLOROFURO[3,2-C]PYRIDINE
CAS No.: 31270-80-1
Chemical Name: 4-CHLOROFURO[3,2-C]PYRIDINE
Synonyms: 104328;Compound Fr13857;SALOR-INT L299537-1EA;4-CHLOROFURO[3,2-]PYRIDINE;4-CHLOROFURO[3,2-C]PYRIDINE;1. 4-Chlorofuro[3,2-C]Pyridine;Furo[3,2-c]pyridine, 4-chloro-;4-Chlorofuro[3,2-c]pyridine HCl;4-CHLOROFURO[3,2-C]PYRIDINE 97%;4-Chlorofuro[3,2-c]pyridine, 95+%
CBNumber: CB4758057
Molecular Formula: C7H4ClNO
Formula Weight: 153.57
MOL File: 31270-80-1.mol

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4-CHLOROFURO[3,2-C]PYRIDINE Property

Melting point:: 41 °C
Boiling point:: 243℃
Density: 1.377
Flash point:: 101℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: -0.69±0.30(Predicted)
color: Orange
InChI: InChI=1S/C7H4ClNO/c8-7-5-2-4-10-6(5)1-3-9-7/h1-4H
InChIKey: OPFFYLJLHPZSEO-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=CC2OC=CC1=2

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
Hazard Note: Irritant
HS Code: 2932190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 4H56-5-J1
Product name: 4-Chlorofuro[3,2-c]pyridine
Packaging: 250mg
Price: $39
Updated: 2021/12/16

Matrix Scientific

Product number: 073947
Product name: 4-Chlorofuro[3,2-c]pyridine
Purity: 95+%
Packaging: 1g
Price: $50
Updated: 2021/12/16

Oakwood

Product number: 067601
Product name: 4-Chlorofuro[3,2-c]pyridine
Purity: 97%
Packaging: 1g
Price: $60
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-5-J1
Product name: 4-Chlorofuro[3,2-c]pyridine
Packaging: 1g
Price: $66
Updated: 2021/12/16

Activate Scientific

Product number: AS5110-A
Product name: 4-Chlorofuro[3,2-c]pyridine
Purity: 95+%
Packaging: 1g
Price: $76
Updated: 2021/12/16

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4-CHLOROFURO[3,2-C]PYRIDINE Chemical Properties,Usage,Production

Definition

ChEBI: 4-Chlorofuro[3,2-c]pyridine is a furopyridine.

Synthesis

26956-43-4

31270-80-1

General procedure for the synthesis of 4-chlorofuranylpyridine from 4,5-dihydro-4-oxofuro[3,2]pyridine: cf. Example 4 Synthesis of 4-chlorofuro[3,2-c]pyridine. 4,5-Dihydro-4-oxofuro[3,2]pyridine (72.2 g, 534 mmol) was added to phosphorochloridic acid (100 mL) preheated to 120 °C with continuous stirring for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Ice-cooled water was added to the residue and the pH was adjusted to basic with 8 M aqueous sodium hydroxide, followed by extraction with ethyl acetate. The organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was again removed by distillation under reduced pressure and the resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=30/70) to afford the target product 4-chlorofuranylpyridine (66.1 g, 81% yield). The product was characterized by 1H-NMR (CDCl3): δ 7.13 (1H, dd, J = 2.2, 1.0 Hz), 7.79 (1H, dd, J = 5.8, 1.0 Hz), 8.27 (1H, d, J = 2.2 Hz), 8.32 (1H, d, J = 5.8 Hz).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 1, p. 250 - 254
[2] Journal of Medicinal Chemistry, 1989, vol. 32, # 6, p. 1147 - 1156
[3] Patent: EP2100895, 2009, A1. Location in patent: Page/Page column 44-45
[4] Bulletin de la Societe Chimique de France, 1971, p. 1727 - 1730
[5] Archiv der Pharmazie, 1981, vol. 314, # 2, p. 156 - 162

4-CHLOROFURO[3,2-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLOROFURO[3,2-C]PYRIDINE Suppliers

Belgium 1 China 113 Germany 4 India 2 United Kingdom 3 United States 17 Global 140

Shanghai TBBMed Co.,Ltd

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J & K SCIENTIFIC LTD.

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Beijing Ouhe Technology Co., Ltd

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Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

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Shangchem Co., Ltd.

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Pure Chemistry Scientific Inc.

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Shanghai Longsheng chemical Co.,Ltd.

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China DongFan Chemical Co.,LTD

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View Lastest Price from 4-CHLOROFURO[3,2-C]PYRIDINE manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.

Product: 4-CHLOROFURO[3,2-C]PYRIDINE 31270-80-1
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 98%
Supply Ability: 100kg
Release date: 2023-03-09

Dideu Industries Group Limited

Product: 4-CHLOROFURO[3,2-C]PYRIDINE 31270-80-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

Career Henan Chemical Co

Product: 4-CHLOROFURO[3,2-C]PYRIDINE 31270-80-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-31

31270-80-1, 4-CHLOROFURO[3,2-C]PYRIDINERelated Search:

OTAVA-BB 1199329 5-Bromofuro[2,3-b]pyridine Furo[2,3-b]pyridine Furo[3,2-b]pyridine,4-oxide(9CI) furo[3,2-b]pyridine Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) 2-b]pyridine Furo[3,2-c]pyridine 4-chlorofuro[3,2-c]pyridine-7-carboxylicacid Furo[3,2-c]pyridine-2-carboxaldehyde (9CI) Ethanone, 1-furo[2,3-b]pyridin-5-yl- (9CI) 4-CHLOROFURO[3,2-C]PYRIDINE 7-CHLOROFURO[2,3-C]PYRIDINE 3-(Carboxymethyl)-6-chlorofuro[3,2-b]pyridine-2-carboxylic acid 2-(Carboxymethyl)-6-chlorofuro[3,2-b]pyridine-3-carboxylic acid AKOS 92637 SALOR-INT L299553-1EA

SALOR-INT L299537-1EA

4-CHLOROFURO[3,2-]PYRIDINE

4-Chlorofuro[3,2-c]pyridine, 95+%

1. 4-Chlorofuro[3,2-C]Pyridine

4-CHLOROFURO[3,2-C]PYRIDINE

4-Chlorofuro[3,2-c]pyridine HCl

4-Chloro-5-azabenzo[b]furan, 4-Chloro-5-aza-1-benzofuran

104328

Furo[3,2-c]pyridine, 4-chloro-

4-CHLOROFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH

Compound Fr13857

4-CHLOROFURO[3,2-C]PYRIDINE 97%

31270-80-1

Heterocycles series

Halides

Fused Ring Systems