ChemicalBook > CAS DataBase List > MART-1 (27-35) (human)

MART-1 (27-35) (human)

Product Name: MART-1 (27-35) (human)
CAS No.: 156251-11-5
Chemical Name: MART-1 (27-35) (human)
Synonyms: MELAN A;AAGIGILTV;H2N-AAGIGILTV-OH;Mouse melanocytes;MART-1 (27-35), HUMAN;MELAN-A/MART-1 (27-35);Rabbit Anti-Melan A antibody;MART-1 (27-35) [HOMO SAPIENS];MART-1 (27-35) (huMan) Melan A;Melan-A, MART-1 (27-35) - 1 mg
CBNumber: CB4766849
Molecular Formula: C37H67N9O11
Formula Weight: 813.98
MOL File: 156251-11-5.mol

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MART-1 (27-35) (human) Property

Boiling point:: 1211.9±65.0 °C(Predicted)
Density: 1.184±0.06 g/cm3(Predicted)
storage temp.: -15°C
form: lyophilized powder
pka: 3.32±0.10(Predicted)
color: white
Water Solubility: water, double-distilled: soluble

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Hazard and Precautionary Statements (GHS)

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MART-1 (27-35) (human) Chemical Properties,Usage,Production

Uses

MART-1 (27-35) (human) is an immunogenic epitope recognized by HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL)[1].

Biological Activity

Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma.

References

[1] Kawakami Y, et al. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J Exp Med. 1994 Jul 1;180(1):347-52. DOI:10.1084/jem.180.1.347
[2] Nolte A, et al. Allogeneic Cell Therapy with Antigen-Specific Cytotoxic T Lymphocytes (CTL) for Malignant Melanoma[M]//Transplantation in Hematology and Oncology II. Springer, Berlin, Heidelberg, 2003: 37-40.

MART-1 (27-35) (human) Preparation Products And Raw materials

Raw materials

Preparation Products

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