4-PHENOXYPHTHALONITRILE

Product Name: 4-PHENOXYPHTHALONITRILE
CAS No.: 38791-62-7
Chemical Name: 4-PHENOXYPHTHALONITRILE
Synonyms: ROXA-013;NSC 646245;4-PHENOXYPHTHALONITRILE;4-phenoxybenzene-1,2-dinitrile;4-Phenoxy-1,2-benzenedicarbonitrile;RSYY（Cyclobenzaprine hydrochloride)-5;1,2-Benzenedicarbonitrile, 4-phenoxy-
CBNumber: CB4770941
Molecular Formula: C14H8N2O
Formula Weight: 220.23
MOL File: 38791-62-7.mol

More

Less

4-PHENOXYPHTHALONITRILE Property

Melting point:: 98-100 °C(lit.)
Boiling point:: 399.8±37.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder, crystals or chunks
Appearance: Off-white to yellow Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 411930
Product name: 4-Phenoxyphthalonitrile
Purity: 98%
Packaging: 1g
Price: $105.23
Updated: 2025/07/31

Sigma-Aldrich

Product number: 411930
Product name: 4-Phenoxyphthalonitrile
Purity: 98%
Packaging: 5g
Price: $399.9
Updated: 2025/07/31

TRC

Product number: P301600
Product name: 4-Phenoxyphthalonitrile
Packaging: 1g
Price: $140
Updated: 2021/12/16

Usbiological

Product number: 019375
Product name: 4-Phenoxyphthalonitrile
Packaging: 1g
Price: $425
Updated: 2021/12/16

Chem-Impex

Product number: 41873
Product name: 4-Phenoxyphthalonitrile,≥97.5%(GC),suitableforHematology&Histology
Purity: ≥97.5%(GC)
Packaging: 1G
Price: $85.03
Updated: 2021/12/16

More

Less

4-PHENOXYPHTHALONITRILE Chemical Properties,Usage,Production

Uses

4-Phenoxyphthalonitrile is a C4-substituted phthalonitrile with monoamine oxidase inhibitory activity. 4-Phenoxyphthalonitrile is used in organic pigments and dyes. Dyes and metabolites.

Synthesis

31643-49-9

108-95-2

38791-62-7

General procedure for the synthesis of 4-phenoxyphthalonitrile from 4-nitrophthalonitrile and phenol: To a solution of tetrahydrofuran (THF, 15 mL) containing sodium hydride (NaH, 0.15 g) and phenol (0.353 g, 0.0375 mol), slowly add 4-nitrophthalonitrile (0.50 g, 0.0028 mol) to the THF (15 mL ) solution. The reaction mixture was heated to reflux for 8 hours. Upon completion of the reaction, 1,2-diisocyano-4-phenoxybenzene (8) was obtained by filtration and the solid was washed with ethyl acetate. The filtrate and washings were combined and the solvent was removed by evaporation under reduced pressure. The white precipitate obtained was purified by fast column chromatography using ethyl acetate: hexane (1:4) as eluent. The yield was 0.737 g in 86.4% with an Rf value of 0.36 (ethyl acetate: hexane, 1:4).1H NMR (300 MHz, CDCl3) δ 0.90 (s, 2H), 3.46 (m, 5H, CH), 7.07 (m, 3H, ArH).13C NMR (300 MHz, CDCl3) δ 71.01, 117.45, 119.69, 119.92, 126.95, 127.34, 134.43, 135.20.

References

[1] Asian Journal of Chemistry, 2017, vol. 29, # 3, p. 489 - 495
[2] Russian Journal of Organic Chemistry, 2006, vol. 42, # 4, p. 603 - 606
[3] Journal of Photochemistry and Photobiology A: Chemistry, 2010, vol. 209, # 2-3, p. 232 - 237
[4] Bioorganic Chemistry, 2012, vol. 40, # 1, p. 114 - 124
[5] Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 6.2, p. 964 - 967

4-PHENOXYPHTHALONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-PHENOXYPHTHALONITRILE Suppliers

Canada 1 China 51 France 1 Germany 1 India 2 Japan 1 Switzerland 1 United Kingdom 1 United States 10 Global 69

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Aloespharm Co., Ltd.

Tel: 021-20960837
Fax: 021-20960837
Email: market@aloespharm.com
Country: China
ProdList: 1302
Advantage: 55

More

Less

View Lastest Price from 4-PHENOXYPHTHALONITRILE manufacturers

Career Henan Chemical Co

Product: 4-PHENOXYPHTHALONITRILE 38791-62-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

38791-62-7, 4-PHENOXYPHTHALONITRILERelated Search:

Hydroquinone 3-PHENOXYPHTHALONITRILE 4-(1H-1,2,3-benzotriazol-1-yl)-5-phenoxyphthalonitrile 3-PHENOXYPHTHALONITRILE 98,3-PHENOXYPHTHALONITRILE 98% Phthalonitrile 4-METHOXYPHTHALONITRILE 3-Methoxybenzonitrile 3-PHENOXYBENZONITRILE 4-(4-ALPHA-CUMYLPHENOXY)PHTHALONITRILE 4-METHOXY-2-METHYLBENZONITRILE 4-(4-FORMYLPHENOXY)PHTHALONITRILE 4-Hydroxyphthalonitrile 3-Cyanophenol 4-(2',6'-DIMETHYLPHENOXY)PHTHALONITRILE 4-PHENOXYPHTHALONITRILE 4-PHENOXYBENZONITRILE

4-PHENOXYPHTHALONITRILE

4-Phenoxy-1,2-benzenedicarbonitrile

NSC 646245

4-phenoxybenzene-1,2-dinitrile

ROXA-013

1,2-Benzenedicarbonitrile, 4-phenoxy-

RSYY（Cyclobenzaprine hydrochloride)-5

38791-62-7

C14H8ON2

C6H5OC6H312CN2

P

Stains and Dyes

Stains&Dyes, A to