4-PHENOXYPHTHALONITRILE
- Product Name
- 4-PHENOXYPHTHALONITRILE
- CAS No.
- 38791-62-7
- Chemical Name
- 4-PHENOXYPHTHALONITRILE
- Synonyms
- ROXA-013;NSC 646245;4-PHENOXYPHTHALONITRILE;4-phenoxybenzene-1,2-dinitrile;4-Phenoxy-1,2-benzenedicarbonitrile;RSYY（Cyclobenzaprine hydrochloride)-5;1,2-Benzenedicarbonitrile, 4-phenoxy-
- CBNumber
- CB4770941
- Molecular Formula
- C14H8N2O
- Formula Weight
- 220.23
- MOL File
- 38791-62-7.mol
4-PHENOXYPHTHALONITRILE Property
- Melting point:
- 98-100 °C(lit.)
- Boiling point:
- 399.8±37.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder, crystals or chunks
- Appearance
- Off-white to yellow Solid
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 411930
- Product name
- 4-Phenoxyphthalonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $105.23
- Updated
- 2025/07/31
- Product number
- 411930
- Product name
- 4-Phenoxyphthalonitrile
- Purity
- 98%
- Packaging
- 5g
- Price
- $399.9
- Updated
- 2025/07/31
- Product number
- P301600
- Product name
- 4-Phenoxyphthalonitrile
- Packaging
- 1g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 019375
- Product name
- 4-Phenoxyphthalonitrile
- Packaging
- 1g
- Price
- $425
- Updated
- 2021/12/16
- Product number
- 41873
- Product name
- 4-Phenoxyphthalonitrile,≥97.5%(GC),suitableforHematology&Histology
- Purity
- ≥97.5%(GC)
- Packaging
- 1G
- Price
- $85.03
- Updated
- 2021/12/16
4-PHENOXYPHTHALONITRILE Chemical Properties,Usage,Production
Uses
4-Phenoxyphthalonitrile is a C4-substituted phthalonitrile with monoamine oxidase inhibitory activity. 4-Phenoxyphthalonitrile is used in organic pigments and dyes. Dyes and metabolites.
Synthesis
31643-49-9
108-95-2
38791-62-7
General procedure for the synthesis of 4-phenoxyphthalonitrile from 4-nitrophthalonitrile and phenol: To a solution of tetrahydrofuran (THF, 15 mL) containing sodium hydride (NaH, 0.15 g) and phenol (0.353 g, 0.0375 mol), slowly add 4-nitrophthalonitrile (0.50 g, 0.0028 mol) to the THF (15 mL ) solution. The reaction mixture was heated to reflux for 8 hours. Upon completion of the reaction, 1,2-diisocyano-4-phenoxybenzene (8) was obtained by filtration and the solid was washed with ethyl acetate. The filtrate and washings were combined and the solvent was removed by evaporation under reduced pressure. The white precipitate obtained was purified by fast column chromatography using ethyl acetate: hexane (1:4) as eluent. The yield was 0.737 g in 86.4% with an Rf value of 0.36 (ethyl acetate: hexane, 1:4).1H NMR (300 MHz, CDCl3) δ 0.90 (s, 2H), 3.46 (m, 5H, CH), 7.07 (m, 3H, ArH).13C NMR (300 MHz, CDCl3) δ 71.01, 117.45, 119.69, 119.92, 126.95, 127.34, 134.43, 135.20.
References
[1] Asian Journal of Chemistry, 2017, vol. 29, # 3, p. 489 - 495
[2] Russian Journal of Organic Chemistry, 2006, vol. 42, # 4, p. 603 - 606
[3] Journal of Photochemistry and Photobiology A: Chemistry, 2010, vol. 209, # 2-3, p. 232 - 237
[4] Bioorganic Chemistry, 2012, vol. 40, # 1, p. 114 - 124
[5] Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 6.2, p. 964 - 967
4-PHENOXYPHTHALONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-PHENOXYPHTHALONITRILE manufacturers
- Product
- 4-PHENOXYPHTHALONITRILE 38791-62-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20