ChemicalBook > CAS DataBase List > N,N',N''-TRIACETYLCHITOTRIOSE

N,N',N''-TRIACETYLCHITOTRIOSE

Product Name
N,N',N''-TRIACETYLCHITOTRIOSE
CAS No.
38864-21-0
Chemical Name
N,N',N''-TRIACETYLCHITOTRIOSE
Synonyms
CHITOTRIOSE;[(GlcNAc)3];Chitintriose;N-acetylated Chitotriose;Tri(N-acetylglucosaMine);GlcNAcβ-4GlcNAcβ-4GlcNAc;CHITOTRIOSE, TRI-N-ACETYL;N-AcetylglucosaMine TriMer;Triacetyl-Chitotriose 30mg;WZZVUHWLNMNWLW-RSGPGLJDSA-N
CBNumber
CB4774136
Molecular Formula
C24H41N3O16
Formula Weight
627.59
MOL File
38864-21-0.mol
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N,N',N''-TRIACETYLCHITOTRIOSE Property

Melting point:
271-272°C dec.
Boiling point:
1146.9±65.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
pka
12.72±0.70(Predicted)
BRN 
75249
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Safety

Safety Statements 
24/25
WGK Germany 
3
10-21
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T2144
Product name
N,N′,N′′-Triacetylchitotriose
Purity
≥93% (HPLC)
Packaging
10mg
Price
$257
Updated
2021/03/22
Sigma-Aldrich
Product number
T2144
Product name
N,N′,N′′-Triacetylchitotriose
Purity
≥93% (HPLC)
Packaging
50mg
Price
$1020
Updated
2021/03/22
TCI Chemical
Product number
T2912
Product name
N,N',N''-Triacetylchitotriose
Purity
>98.0%(HPLC)
Packaging
20mg
Price
$367
Updated
2021/03/22
Cayman Chemical
Product number
20759
Product name
N,N',N''-Triacetylchitotriose
Purity
≥95%
Packaging
1mg
Price
$40
Updated
2021/03/22
Cayman Chemical
Product number
20759
Product name
N,N',N''-Triacetylchitotriose
Purity
≥95%
Packaging
5mg
Price
$100
Updated
2021/03/22
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N,N',N''-TRIACETYLCHITOTRIOSE Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Uses

N,N',N''-Triacetylchitotriose is a triose oligosaccharide derived from chitin, consisting of three N-acetylglucosamine units. It has been shown to scavenge reactive oxygen species and to protect DNA from oxidative damage.

Reactions

The hydrolytic activity of lysozyme towards 4-methylumbelliferyl tetra-N-acetyl-β-chitotetraoside (4-MU-(GlcNAc)4) was little affected by ionic strength, though the activity of lysozyme towards cell suspension of Micrococcus lysodeikticus varied markedly with ionic strength. About 40-60percent of lysozyme activity with 4-MU-(GlcNAc)4 as a substrate was inhibited by 0.1 mM N,N',N''-triacetylchitotriose ((GlcNAc)3), but the lytic activity of lysozyme towards M. lysodeikticus was little affected. The kinetics of hydrolysis of 4-MU-(GlcNAc)4 by hen eggwhite (HEW) lysozyme and human placental (HP) lysozyme and the inhibition of this hydrolysis by (GlcNAc)3 were investigated. The K(s) values for 4-MU-(GlcNAc)4 of HEW- and HP-lysozymes were 19.7 and 27.9 μM, respectively, and the V(max) values were 0.124 and 0.0833 nmol/min/mg, respectively. The k values of both enzymes were very low, implying a poor orientation of the scissile bond in the substrate molecule with respect to the active site of lysozyme. (GlcNAc)3 inhibited lysozyme with hyperbolic mixed-type inhibition. The inhibition reduced V(max) values of both lysozymes. The K(s) value of HEW-lysozyme was increased by the addition of the inhibitory whereas the K(s) value of HP-lysozyme was decreased. The K(i) value was 29.6 μm for HEW-lysozyme and 106 μM for HP-lysozyme.

  1. Hydrolysis of 4-methylumbelliferyl tetra-N-acetyl-β-chitotetraoside by lysozyme and its inhibition by N,N',N''-triacetylchitotriose
  2. Tanimoto; Fukuda; Kawamura - Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 9, p. 3607 - 361

N,N',N''-TRIACETYLCHITOTRIOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N',N''-TRIACETYLCHITOTRIOSE Suppliers

J & K SCIENTIFIC LTD.
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010-82848833- ;010-82848833-
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TCI (Shanghai) Development Co., Ltd.
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Japan
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Chengdu HuaXia Chemical Reagent Co. Ltd
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400-1166-196;028-84555506- ;028-84555506-
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38864-21-0, N,N',N''-TRIACETYLCHITOTRIOSERelated Search:


  • Tri(N-acetylglucosaMine)
  • GlcNAcβ(1-4)GlcNAcβ(1-4)GlcNAc
  • N,N',N''-TRIACETYLCHITOTRIOSE
  • N,N',N'-TRIACETYLCHITOTRIOSE
  • O-[2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL-(1->4)]-O-[2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYR-ANOSYL-(1->4)]-2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSE
  • CHITOTRIOSE
  • CHITOTRIOSE, TRI-N-ACETYL
  • GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC
  • GLCNAC1-B-4GLCNAC1-B-4GLCNAC
  • N-acetylated Chitotriose
  • o-[2-acetamido-2-deoxy-β-d-glucopyranosyl-(1→4)]-o-[2-acetamido-2-deoxy-β-d-glucopyranosyl-(1→4)]-2-acetamido-2-deoxy-d-glucopyranose
  • N-[(2R,3R,4R,5R)-4-[(2R,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,6-trihydroxy-1-oxo-hexan-2-yl]acetamide
  • N,N′,N′′-Triacetylchitotriose,O-[2-Acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)]-O-[2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)]-2-acetamido-2-deoxy-D-glucopyranose
  • N,N',N''-Triacetylchitotriose ,95%
  • [(GlcNAc)3]
  • N-AcetylglucosaMine TriMer
  • WZZVUHWLNMNWLW-RSGPGLJDSA-N
  • Triacetyl-Chitotriose 30mg
  • D-Glucose, O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-
  • Chitintriose
  • GlcNAcβ-4GlcNAcβ-4GlcNAc
  • N,N',N''-TRIACETYLCHITOTRIOSE USP/EP/BP
  • 38864-21-0
  • C24H41N3O16
  • Oligosaccharide
  • BioChemical
  • Biochemicals and Reagents
  • Carbohydrates
  • Oligosaccharides