ChemicalBook > CAS DataBase List > N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose

N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose

Product Name
N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose
CAS No.
38854-46-5
Chemical Name
N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose
Synonyms
nacos-6;Brn 0001006;n-acetylchitohexaose;N-acetylated chitohexaose;chitohexaose,hexa-n-acetyl;n-acetylglucosaminehexamer;HEXA-(N-ACETYL) CHITOHEXAOSE;Hexaacetyl-Chitohexaose- 10mg;N,N,N,N,N-Hexaacetylchitohexaose;Chitohexaose, hexa-N-acetyl (6ci)
CBNumber
CB8304793
Molecular Formula
C48H80N6O31
Formula Weight
1237.17
MOL File
38854-46-5.mol
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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Property

Melting point:
>250°C (dec.)
alpha 
-11.4 º (in H2O)
Boiling point:
1652.6±65.0 °C(Predicted)
Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Water (Slightly), Methanol (Slightly)
form 
Solid
pka
12.72±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ6653000
HS Code 
29400090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
1mg
Price
$218
Updated
2024/03/01
Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
5mg
Price
$601
Updated
2024/03/01
TRC
Product number
H290750
Product name
N,N’,N’’,N’’’,N’’’’,N’’’’’-Hexaacetylchitohexaose
Packaging
10mg
Price
$1015
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0000532
Product name
N,N',N'',N''',N'''',N'''''-HEXAACETYLCHITOHEXAOSE
Purity
95.00%
Packaging
10MG
Price
$1871.1
Updated
2021/12/16
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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

cation exchanger ~1.4 meq/g

Uses

Various publications have cited the use of N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose in mutagenesis studies due to its antitumor effects.
Hexa-N-acetylchitohexaose is a hexamer of N-acetylglucosamine, a subunit of the natural polymer chitin. It functions as an elicitor in plants, inducing the expression of chitinases.Like chitin and some of its derivatives, hexa-N-acetylchitohexaose is a substrate of lysozyme.It also binds LysM domains on certain proteins, including an endopeptidase of T. thermophilus.Hexa-N-acetylchitohexaose heightens the immune response against Pseudomonas and Listeria in mice, stimulates cytokine secretion in mesenchymal stem cells, and inhibits nitric oxide production by activated macrophages.

Uses

Studied for anti-tumor effects

Reactions

Chitohexaose has attracted wide interest due to its special bioactivities and these potential activities are significantly related to N-acetylation.
Herein, six chitohexaose fractions with different degrees of acetylation were prepared by selective N-acetylation and ion-exchange chromatography and further analyzed by ESI/MS.
It is revealed that all the six N-acetylated chitohexaoses were of single molecular weight, the molecular weights of which were exactly assigned to 1026.44 Da, 1068.44 Da, 1110.48 Da, 1152.48 Da, 1194.49 Da, and 1236.48 Da, respectively. These results suggested that the six prepared N-acetylated chitohexaoses were N-acetylchitohexaose (D5A1), di-N-acetylchitohexaose (D4A2), tri-N-acetylchitohexaose (D3A3), tetra-N-acetylchitohexaose (D2A4), penta-N-acetylchitohexaose (D1A5), and hexa-N-acetylchitohexaose (A6), respectively, which are of great significance to screen their bioactivities and discover well-defined chitooligosaccharide molecules as potential drugs.

  1. Access to N-acetylated chitohexaose with well-defined degrees of acetylation
  2. Li, Kecheng; Xing, Ronge; Liu, Song; Qin, Yukun; Li, Pengcheng - BioMed Research International, 2017, vol. 2017

N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Suppliers

Qingdao Bz Oligo Biotech Co., Ltd.
Tel
0532-81926027 13045058792
Fax
0532-81926219
Email
june@marine-oligo.com
Country
China
ProdList
102
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973185 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Jinan Feiteng Pharmaceutical Technology Co., Ltd.
Tel
15589964716
Fax
qq:3360232875
Email
15253102672@163.com
Country
China
ProdList
211
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-62971590 18548936886
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
6912
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
21450
Advantage
58
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View Lastest Price from N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N,N,N,N,N,N-Hexaacetylchitohexaose 38854-46-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19

38854-46-5, N,N',N'',N''',N'''',N'''''-HexaacetylchitohexaoseRelated Search:


  • HEXA-(N-ACETYL) CHITOHEXAOSE
  • GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC
  • GLCNAC1-B-4-GLCNAC1-B-4-GLCNAC1-B-4GLCNAC1-B-4GLCNAC1-B-4GLCNAC
  • N,N',N'',N''',N'''',N'''''-Hexa-O-acetylchitohexaose
  • Brn 0001006
  • Chitohexaose, hexa-N-acetyl (6ci)
  • D-Glucose, o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-
  • N-acetylated chitohexaose
  • O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose
  • cetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-
  • chitohexaose,hexa-n-acetyl
  • d-glucose,o-2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(acetylami
  • n-acetylchitohexaose
  • n-acetylglucosaminehexamer
  • n-acetylglucosaminehexasaccharide
  • nacos-6
  • no)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-d-gluc
  • opyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(a
  • N(I),N(II),N(III),N(IV),N(V),N(VI)-HEXAACETYLCHITOHEXAOSE
  • N,N',N'',N''',N'''',N'''''-HEXAACETYL CHITOHEXAOSE
  • N,N',N,N''',N'''',N'''''-HEXAACETYLCHITOHEXAOSE
  • N,N,N,N,N-Hexaacetylchitohexaose
  • Hexaacetyl-Chitohexaose- 10mg
  • D-Glucose, O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-
  • N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose USP/EP/BP
  • 38854-46-5
  • C48H80N6O31
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Immune Cell Signaling and Blood
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Oligosaccharides