C16-PHYTOCERAMIDE

Product Name: C16-PHYTOCERAMIDE
CAS No.: 111149-09-8
Chemical Name: C16-PHYTOCERAMIDE
Synonyms: armillaramide.;C16-PHYTOCERAMIDE;N-16:0 Phytosphingosine;C16 Phytoceramide (t18:0/16:0);N-HEXADECANOYL-PHYTOSPHINGOSINE;N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-hexadecanamide;Hexadecanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-
CBNumber: CB4793069
Molecular Formula: C34H69NO4
Formula Weight: 555.92
MOL File: 111149-09-8.mol

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C16-PHYTOCERAMIDE Property

storage temp.: Store at -20°C, protect from light
solubility: Chloroform:Methanol (5:1): soluble
form: A solid
InChIKey: IVBULNXGVIHEKN-MVIDNBQJSA-N
SMILES: O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22826
Product name: C16 Phytoceramide (t18:0/16:0)
Purity: ≥98%
Packaging: 5mg
Price: $178
Updated: 2024/03/01

AK Scientific

Product number: 8019CR
Product name: N-(Palmitoyl)-phytoceramide
Packaging: 5mg
Price: $349
Updated: 2021/12/16

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C16-PHYTOCERAMIDE Chemical Properties,Usage,Production

Description

C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. [Matreya, LLC. Catalog No. 2035]

Uses

Armillaramide (Desulfated ircisulfamide) is an ester product.

Definition

ChEBI: N-hexadecanoylphytosphingosine is a phytoceramide compound having a hexadecanoyl group attached to the nitrogen atom. It is a N-acylphytosphingosine and a N-palmitoyl-sphingoid base.

References

[1] M. W. CROSSMAN C H. Biosynthesis of phytosphingosine by the rat.[J]. The Journal of Biological Chemistry, 1977, 22 1: 5815-5819. DOI: 10.1016/s0021-9258(17)40095-0
[2] YUKIKO MIZUTANI Yasuyuki I Akio Kihara. Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation[J]. FEBS Letters, 2004, 563 1: Pages 93-97. DOI: 10.1016/s0014-5793(04)00274-1
[3] DAVID J. MONTEFUSCO. Distinct Signaling Roles of Ceramide Species in Yeast Revealed Through Systematic Perturbation and Systems Biology Analyses[J]. Science Signaling, 2013, 6 299. DOI: 10.1126/scisignal.2004515
[4] MIRANDA DE JAGER . Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies[J]. Biochimica et biophysica acta. Biomembranes, 2006, 1758 5: Pages 636-644. DOI: 10.1016/j.bbamem.2006.04.001
[5] LINE HOLLESEN BASSE Joke A B Dani?l Groen. Permeability and lipid organization of a novel psoriasis stratum corneum substitute[J]. International Journal of Pharmaceutics, 2013, 457 1: Pages 275-282. DOI: 10.1016/j.ijpharm.2013.08.086

C16-PHYTOCERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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C16-PHYTOCERAMIDE Suppliers

China 14 United States 6 Global 20

Alfa Chemistry

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SuZhou Medinoah Co.,LTD.

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amyjet

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Cayman Chemical Company

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Merck KGaA

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Aikon International Limited

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111149-09-8, C16-PHYTOCERAMIDERelated Search:

Phytosphingosine

C16 Phytoceramide (t18:0/16:0)

C16-PHYTOCERAMIDE

N-HEXADECANOYL-PHYTOSPHINGOSINE

N-16:0 Phytosphingosine

Hexadecanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-

N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-hexadecanamide

armillaramide.

111149-09-8

C34H69NO4