ChemicalBook > CAS DataBase List > N-Desethylsunitinib hydrochloride
N-Desethylsunitinib hydrochloride
- Product Name
- N-Desethylsunitinib hydrochloride
- CAS No.
- 1261432-05-6
- Chemical Name
- N-Desethylsunitinib hydrochloride
- Synonyms
- N-Desethyl sunitinib HCl;N-Desethylsunitinib hydrochloride;N-Desethylsunitinib hydrochloride, 10 mM in DMSO;N Desethylsunitinib hydrochloride,NDesethylsunitinib hydrochloride
- CBNumber
- CB48042165
- Molecular Formula
- C20H24ClFN4O2
- Formula Weight
- 406.89
- MOL File
- 1261432-05-6.mol
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N-Desethylsunitinib hydrochloride Property
- form
- Solid
- color
- Yellow to brown
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N-Desethylsunitinib hydrochloride Chemical Properties,Usage,Production
Uses
(E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP[1].
References
[1] Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase DOI:10.1021/jm0204183
N-Desethylsunitinib hydrochloride Preparation Products And Raw materials
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