ChemicalBook > CAS DataBase List > E3 ligase Ligand 18
E3 ligase Ligand 18
- Product Name
- E3 ligase Ligand 18
- CAS No.
- 2241669-88-3
- Chemical Name
- E3 ligase Ligand 18
- Synonyms
- E3 ligase Ligand 18;L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]-;(R)-2-Acetamido-3-((2-amino-9-(4-chlorobenzyl)-6-oxo-6,9-dihydro-3H-purin-8-yl)thio)propanoic acid;(2R)-3-({2-amino-9-[(4-chlorophenyl)methyl]-6-oxo-6,9-dihydro-3H-purin-8-yl}sulfanyl)-2-acetamidopropanoic acid
- CBNumber
- CB48054708
- Molecular Formula
- C17H17ClN6O4S
- Formula Weight
- 436.87
- MOL File
- 2241669-88-3.mol
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E3 ligase Ligand 18 Property
- Density
- 1.68±0.1 g/cm3(Predicted)
- pka
- 3.17±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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E3 ligase Ligand 18 Chemical Properties,Usage,Production
Uses
E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
IC 50
Cereblon
References
[1] Heterocyclic compound. WO2018143403A1.
E3 ligase Ligand 18 Preparation Products And Raw materials
Raw materials
Preparation Products
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E3 ligase Ligand 18 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
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