PROTAC Linker 27

Product Name: PROTAC Linker 27
CAS No.: 1246286-33-8
Chemical Name: PROTAC Linker 27
Synonyms: Tos-PEG2-NH2;PROTAC Linker 27;2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate;Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate)
CBNumber: CB48054814
Molecular Formula: C11H17NO4S
Formula Weight: 259.32
MOL File: 1246286-33-8.mol

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PROTAC Linker 27 Property

Boiling point:: 414.5±30.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
pka: 8?+-.0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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PROTAC Linker 27 Chemical Properties,Usage,Production

Biological Activity

Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

PROTAC Linker 27 Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTAC Linker 27 Suppliers

China 6 United States 1 Global 7

TargetMol Chemicals Inc.

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1246286-33-8, PROTAC Linker 27Related Search:

PROTAC Linker 27

Tos-PEG2-NH2

2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate

Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate)

1246286-33-8

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