LDC7559

Product Name: LDC7559
CAS No.: 2407782-01-6
Chemical Name: LDC7559
Synonyms: LDC7559;Inhibitor,Pyroptosis,LDC7559,inhibit,LDC 7559,LDC-7559;Acetamide, N-[2-(2-methoxyphenyl)-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl]-;N-(2-(2-Methoxyphenyl)-4,10-dihydrobenzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide
CBNumber: CB48096799
Molecular Formula: C20H19N3O3
Formula Weight: 349.38
MOL File: 2407782-01-6.mol

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LDC7559 Property

Boiling point:: 596.3±50.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 125 mg/mL (357.78 mM)
pka: 14.44±0.20(Predicted)
form: Solid
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0089815
Product name: LDC7559
Purity: 99.64%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0089815
Product name: LDC7559
Purity: 99.64%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0089815
Product name: LDC7559
Purity: 99.64%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0089815
Product name: LDC7559
Purity: 99.64%
Packaging: 100mg
Price: $2300
Updated: 2021/12/16

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LDC7559 Chemical Properties,Usage,Production

Description

LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages.

in vitro

LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells.
LDC7559 functions directly through blocking the activity of the GSDMD NT domain, rather than interfering with the activation and cleavage process.

LDC7559 Preparation Products And Raw materials

Raw materials

Preparation Products

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LDC7559 Suppliers

China 17 United States 3 Global 20

Nanjing Xinmeihe Pharmaceutical Co., Ltd.

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2407782-01-6, LDC7559Related Search:

Sovilnesib

Acetamide, N-[2-(2-methoxyphenyl)-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl]-

LDC7559

Inhibitor,Pyroptosis,LDC7559,inhibit,LDC 7559,LDC-7559

N-(2-(2-Methoxyphenyl)-4,10-dihydrobenzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide

2407782-01-6