(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE

Product Name: (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE
CAS No.: 1218935-60-4
Chemical Name: (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE
Synonyms: (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HCL;(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE;(R)-2-(2,5-Difluorophenyl)pyrrolidene hydrochloride;Pyrrolidine, 2-(2,5-difluorophenyl)-, hydrochloride (1:1), (2R)-;(R)-2-(2,5-difluorophenyl)pyrrolidine (HCL salt form), 97%min, ee97%min
CBNumber: CB4816500
Molecular Formula: C10H12ClF2N
Formula Weight: 219.66
MOL File: Mol file

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(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE Property

storage temp.: Sealed in dry,Room Temperature
Appearance: Off-white to light yellow Solid
InChI: InChI=1/C10H11F2N.ClH/c11-7-3-4-9(12)8(6-7)10-2-1-5-13-10;/h3-4,6,10,13H,1-2,5H2;1H/t10-;/s3
InChIKey: XSWCQOVADZHFIJ-MEQOOBBNNA-N
SMILES: FC1C=CC(F)=CC=1[C@@H]1NCCC1.Cl |&1:8,r|

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: R701405
Product name: (R)-2-(2,5-difluorophenyl)pyrrolidinehydrochloride
Packaging: 50mg
Price: $175
Updated: 2021/12/16

Apolloscientific

Product number: PC201077
Product name: (R)-2-(2,5-Difluorophenyl)pyrrolidinehydrochloride
Purity: 95+%
Packaging: 100mg
Price: $94
Updated: 2021/12/16

Apolloscientific

Product number: PC201077
Product name: (R)-2-(2,5-Difluorophenyl)pyrrolidinehydrochloride
Purity: 95+%
Packaging: 250mg
Price: $116
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H31-7-R3
Product name: (R)-2-(2,5-Difluorophenyl)pyrrolidinehydrochloride
Purity: 95.0%
Packaging: 100mg
Price: $151
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H31-7-R3
Product name: (R)-2-(2,5-Difluorophenyl)pyrrolidinehydrochloride
Purity: 95.0%
Packaging: 250mg
Price: $186
Updated: 2021/12/16

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(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

1443538-31-5

1218935-60-4

The general procedure for the synthesis of (R)-2-(2,5-difluorophenyl)pyrrolidine hydrochloride from the compound (CAS: 1443538-31-5) was as follows: to a stirred solution of (R)-1-((S)-tert-butylsulfinyl)-2-(2,5-difluorophenyl)pyrrolidine (15 g, 52.19 mmol) in dioxane (25 mL) was added a 4 M HCl to a solution of dioxane (75 mL). The reaction mixture was stirred continuously at 20-35°C for 4 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to give the crude product. The crude product was purified by washing with ether to give 7.5 g of (R)-2-(2,5-difluorophenyl)pyrrolidine hydrochloride as a white solid. Mass spectrometry (ESI) analysis showed: m/z 184 (M + H).

References

[1] Patent: WO2013/88256, 2013, A1. Location in patent: Page/Page column 59
[2] Patent: US2014/371217, 2014, A1. Location in patent: Paragraph 0561
[3] Patent: US2015/5280, 2015, A1. Location in patent: Paragraph 0527 - 0529
[4] Patent: US2015/368238, 2015, A1. Location in patent: Paragraph 0574; 0579

(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE Suppliers

China 153 India 2 United States 6 Global 161

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View Lastest Price from (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride 1218935-60-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-06

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE 1218935-60-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Nanjing Fred Technology Co., Ltd

Product: (R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride 1218935-60-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-26

1218935-60-4, (R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDERelated Search:

(2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE

(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE

(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HCL

(R)-2-(2,5-Difluorophenyl)pyrrolidene hydrochloride

Pyrrolidine, 2-(2,5-difluorophenyl)-, hydrochloride (1:1), (2R)-

(R)-2-(2,5-difluorophenyl)pyrrolidine (HCL salt form), 97%min, ee97%min

1218935-60-4

218935-60-4

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