ChemicalBook > CAS DataBase List > 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE

3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE

Product Name
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
CAS No.
573675-27-1
Chemical Name
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
Synonyms
3-Amino-5-bromopicolinonitrile;3-Amino-5-bromo-2-cyanopyridine;3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 3-amino-5-bromo-;3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE ISO 9001:2015 REACH
CBNumber
CB4822000
Molecular Formula
C6H4BrN3
Formula Weight
198.02
MOL File
573675-27-1.mol
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3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Property

Boiling point:
376.5±42.0 °C(Predicted)
Density 
1.80±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
-1.28±0.10(Predicted)
form 
solid
color 
Brown
InChI
InChI=1S/C6H4BrN3/c7-4-1-5(9)6(2-8)10-3-4/h1,3H,9H2
InChIKey
WDKOOTHLXCMQGH-UHFFFAOYSA-N
SMILES
C1(C#N)=NC=C(Br)C=C1N
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000135
Product name
3-Amino-5-bromopicolinonitrile
Purity
Aldrich
Packaging
1g
Price
$817
Updated
2025/07/31
TRC
Product number
A595903
Product name
3-amino-5-bromopyridine-2-carbonitrile
Packaging
500mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA139429
Product name
3-Amino-5-bromopicolinonitrile
Packaging
1g
Price
$63
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA139429
Product name
3-Amino-5-bromopicolinonitrile
Packaging
2g
Price
$110
Updated
2021/12/16
Apolloscientific
Product number
OR959411
Product name
3-Amino-5-bromopyridine-2-carbonitrile
Purity
98%
Packaging
1g
Price
$110
Updated
2021/12/16
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3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Chemical Properties,Usage,Production

Synthesis

573675-25-9

573675-27-1

Step 1: 5-bromo-2-cyano-3-nitropyridine (K1, 5 g, 21.9 mmol) was dissolved in cooled concentrated hydrochloric acid (30 mL), and tin chloride dihydrate (SnCl2-2H2O, 24.7 g, 109.5 mmol) was added in batches. After the addition was completed, the reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio PE:EA = 3:1) to confirm the completion of the reaction. Subsequently, the mixture was alkalized with aqueous sodium carbonate and extracted with ethyl acetate. The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated and the resulting residue was purified by column chromatography (eluent ratio PE:EA = 20:1 to 5:1) to afford 3-amino-5-bromopyridine-2-carbonitrile (K2, 1.9 g). Mass spectrometry (MS) analysis showed molecular ion peaks m/e = 198 and 200 (M + 1) for K2.

References

[1] Patent: WO2005/42498, 2005, A2. Location in patent: Page/Page column 44
[2] Patent: WO2011/51540, 2011, A1. Location in patent: Page/Page column 74
[3] Patent: WO2016/118404, 2016, A1. Location in patent: Page/Page column 46; 47

3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Suppliers

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View Lastest Price from 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE manufacturers

Dideu Industries Group Limited
Product
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE 573675-27-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-23
Shaanxi Dideu Medichem Co. Ltd
Product
3-Amino-5-Bromopicolinonitrile 573675-27-1
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12

573675-27-1, 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILERelated Search:


  • 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
  • 3-Amino-5-bromopicolinonitrile
  • 2-Pyridinecarbonitrile, 3-amino-5-bromo-
  • 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE ISO 9001:2015 REACH
  • 3-Amino-5-bromo-2-cyanopyridine
  • 573675-27-1