3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
- Product Name
- 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
- CAS No.
- 573675-27-1
- Chemical Name
- 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
- Synonyms
- 3-Amino-5-bromopicolinonitrile;3-Amino-5-bromo-2-cyanopyridine;3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 3-amino-5-bromo-;3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE ISO 9001：2015 REACH
- CBNumber
- CB4822000
- Molecular Formula
- C6H4BrN3
- Formula Weight
- 198.02
- MOL File
- 573675-27-1.mol
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Property
- Boiling point:
- 376.5±42.0 °C(Predicted)
- Density
- 1.80±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- -1.28±0.10(Predicted)
- form
- solid
- color
- Brown
- InChI
- InChI=1S/C6H4BrN3/c7-4-1-5(9)6(2-8)10-3-4/h1,3H,9H2
- InChIKey
- WDKOOTHLXCMQGH-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=C(Br)C=C1N
N-Bromosuccinimide Price
- Product number
- ADE000135
- Product name
- 3-Amino-5-bromopicolinonitrile
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $817
- Updated
- 2025/07/31
- Product number
- A595903
- Product name
- 3-amino-5-bromopyridine-2-carbonitrile
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FA139429
- Product name
- 3-Amino-5-bromopicolinonitrile
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- FA139429
- Product name
- 3-Amino-5-bromopicolinonitrile
- Packaging
- 2g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR959411
- Product name
- 3-Amino-5-bromopyridine-2-carbonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Chemical Properties,Usage,Production
Synthesis
573675-25-9
573675-27-1
Step 1: 5-bromo-2-cyano-3-nitropyridine (K1, 5 g, 21.9 mmol) was dissolved in cooled concentrated hydrochloric acid (30 mL), and tin chloride dihydrate (SnCl2-2H2O, 24.7 g, 109.5 mmol) was added in batches. After the addition was completed, the reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio PE:EA = 3:1) to confirm the completion of the reaction. Subsequently, the mixture was alkalized with aqueous sodium carbonate and extracted with ethyl acetate. The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated and the resulting residue was purified by column chromatography (eluent ratio PE:EA = 20:1 to 5:1) to afford 3-amino-5-bromopyridine-2-carbonitrile (K2, 1.9 g). Mass spectrometry (MS) analysis showed molecular ion peaks m/e = 198 and 200 (M + 1) for K2.
References
[1] Patent: WO2005/42498, 2005, A2. Location in patent: Page/Page column 44
[2] Patent: WO2011/51540, 2011, A1. Location in patent: Page/Page column 74
[3] Patent: WO2016/118404, 2016, A1. Location in patent: Page/Page column 46; 47
3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE manufacturers
- Product
- 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE 573675-27-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-23
- Product
- 3-Amino-5-Bromopicolinonitrile 573675-27-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12