ChemicalBook > CAS DataBase List > 1-BOC-3-(METHOXY)AZETIDINE

1-BOC-3-(METHOXY)AZETIDINE

Product Name
1-BOC-3-(METHOXY)AZETIDINE
CAS No.
429669-07-8
Chemical Name
1-BOC-3-(METHOXY)AZETIDINE
Synonyms
1-Boc-3-(methoxy);N-Boc-3-Methoxyazetidine;1-BOC-3-(METHOXY)AZETIDINE;3-Methoxyazetidine, N-BOC protected;1-Boc-3-methoxyazetidine - [M12191];tert-butyl 3-Methoxyazetidine-1-carboxylate;tert-Butyl 3-methoxy-1-azetidinecarboxylate;1,1-Dimethylethyl 3-methoxy-1-azetidinecarboxylate;3-Methoxy-azetidine-1-carboxylic acid tert-butyl ester;1-Azetidinecarboxylicacid, 3-Methoxy-, 1,1-diMethylethyl ester
CBNumber
CB4840365
Molecular Formula
C9H17NO3
Formula Weight
187.24
MOL File
429669-07-8.mol
More
Less

1-BOC-3-(METHOXY)AZETIDINE Property

Boiling point:
232.8±33.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-2.86±0.40(Predicted)
Appearance
Colorless to light yellow Liquid
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2918199890
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Matrix Scientific
Product number
059934
Product name
1-Boc-3-methoxyazetidine
Purity
95%
Packaging
1g
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
059934
Product name
1-Boc-3-methoxyazetidine
Purity
95%
Packaging
5g
Price
$260
Updated
2021/12/16
AK Scientific
Product number
Z1934
Product name
1-Boc-3-(methoxy)azetidine
Packaging
10g
Price
$344
Updated
2021/12/16
Synthonix
Product number
M12191
Product name
1-Boc-3-methoxyazetidine
Purity
95+%
Packaging
50g
Price
$850
Updated
2021/12/16
Chemenu
Product number
CM105421
Product name
tert-butyl3-methoxyazetidine-1-carboxylate
Purity
95%
Packaging
25g
Price
$407
Updated
2021/12/16
More
Less

1-BOC-3-(METHOXY)AZETIDINE Chemical Properties,Usage,Production

Synthesis

141699-55-0

74-88-4

429669-07-8

To a solution of tetrahydrofuran (THF, 50 mL) of tert-butyl 3-hydroxy-azetidine-1-carboxylate (0.8 g, 4.62 mmol) was added sodium hydride (60% dispersed in mineral oil, 0.74 g, 18.5 mmol). The reaction mixture was stirred at 0 °C for 0.5 h, followed by the slow addition of iodomethane (2.8 mL, 46.2 mmol). The reaction mixture was stirred overnight at room temperature. After completion of the reaction, it was quenched with water (50 mL) and extracted with ethyl acetate (EtOAc, 30 mL x 3). The organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford the target product 3-methoxy-N-Boc-azetidine (0.8 g, 93% yield) as an oil.1H NMR (400 MHz, CDCl3): δ 4.11-4.13 (m, 1H), 4.04-4.08 (m, 2H), 3.79- 3.83 (m, 2H), 3.27 (s, 3H), 1.43 (s, 9H).

References

[1] Organic Letters, 2014, vol. 16, # 3, p. 856 - 859
[2] Patent: WO2013/53690, 2013, A1. Location in patent: Page/Page column 37; 38
[3] Patent: US2004/14962, 2004, A1. Location in patent: Page/Page column 135
[4] Patent: US2008/214815, 2008, A1. Location in patent: Page/Page column 16
[5] Patent: WO2011/63502, 2011, A1. Location in patent: Page/Page column 50

1-BOC-3-(METHOXY)AZETIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-BOC-3-(METHOXY)AZETIDINE Suppliers

Austria 1 China 66 Europe 1 India 1 United Kingdom 1 United States 7 Global 77
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
1009
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Tianjin Chempharmatech Co.,Ltd.
Tel
022-66211079 13212288319
Fax
qq1405432731
Email
sales@chempharmatech.com
Country
China
ProdList
915
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
1941
Advantage
62
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2598
Advantage
60
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
More
Less

View Lastest Price from 1-BOC-3-(METHOXY)AZETIDINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-BOC-3-(METHOXY)AZETIDINE 429669-07-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-BOC-3-(METHOXY)AZETIDINE 429669-07-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
1-BOC-3-(METHOXY)AZETIDINE 429669-07-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
500kg/month
Release date
2019-08-01

429669-07-8, 1-BOC-3-(METHOXY)AZETIDINERelated Search:

N-1-Boc-3-phenylpiperazine 1-BOC-3-METHYL-PIPERIDIN-4-ONE 1-Boc-3-iodoazetidine (3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone (3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate DOCETAXEL SIDE CHAIN NO 1 3-CARBOXYMETHOXY-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-BOC-3-(METHOXY)AZETIDINE 3-(3-Trifluoromethyl-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(2-Fluoro-3-trifluoromethyl-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(4-Trifluoromethoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(3-Trifluoromethoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(2,3-Difluoro-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(2-Chloro-3-trifluoromethyl-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(2-Chloro-5-trifluoromethyl-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(3,5-Bis-trifluoromethyl-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-(2,4-Difluoro-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 3-ACETOXY-BOC-2-AZETIDINONE

  • 1-BOC-3-(METHOXY)AZETIDINE
  • 1-Azetidinecarboxylicacid,3-methoxy-,1,1-dimethylethylester(9CI)
  • 3-Methoxy-azetidine-1-carboxylic acid tert-butyl ester
  • 3-Methoxyazetidine, N-BOC protected
  • tert-Butyl 3-methoxyazetidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-3-methoxyazetidine
  • tert-butyl 3-Methoxyazetidine-1-carboxylate
  • N-Boc-3-Methoxyazetidine
  • 1-Azetidinecarboxylicacid, 3-Methoxy-, 1,1-diMethylethyl ester
  • 1-Boc-3-(methoxy)
  • 1-Azetidinecarboxylicacid, 3-methoxy-, 1,1-dimethylethyl est...
  • 1,1-Dimethylethyl 3-methoxy-1-azetidinecarboxylate
  • 1-Boc-3-methoxyazetidine - [M12191]
  • tert-Butyl 3-methoxy-1-azetidinecarboxylate
  • 429669-07-8
  • METHOXY