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piritramide

Product Name
piritramide
CAS No.
302-41-0
Chemical Name
piritramide
Synonyms
A 65;R 3365;Pirdolan;Piridolan;Dipidolor;Pirtramide;piritramide;Pirinitramide;DipiritraMide;Piritramide (1 mg/mL in Methanol)
CBNumber
CB4893624
Molecular Formula
C27H34N4O
Formula Weight
430.59
MOL File
302-41-0.mol
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piritramide Property

Melting point:
149-150°
Boiling point:
544.82°C (rough estimate)
Density 
1.0967 (rough estimate)
refractive index 
1.5900 (estimate)
storage temp. 
Controlled Substance, -20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
16.19±0.20(Predicted)
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Chemtos
Product number
P-5998
Product name
Piritramide
Packaging
10mg
Price
$1100
Updated
2021/12/16
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piritramide Chemical Properties,Usage,Production

Chemical Properties

Off-White Low Melting Solid

Originator

Dipidolor ,Janssen W. ,Germany,1969

Uses

Piritramide is a synthetic opioid commonly used in Germany and Austria for the analgesia of pediatric patients.

Definition

ChEBI: Piritramide is a nitrile.

Manufacturing Process

A mixture of 84 parts of 3,3-diphenyl-3-cyanopropyl bromide, 41 parts of 4piperidino-4-piperidinecarboxamide, 64 parts of sodium carbonate, a small amount of potassium iodide and 1,200 parts of anhydrous toluene was stirred, and heated under reflux for 48 hours. At the end of this time the reaction mixture was allowed to cool to room temperature, and 500 parts of water were added. The resultant precipitate was removed by filtration, and triturated with diisopropyl ether. The crystalline material thus obtained was removed by filtration, and recrystallized from 320 parts of acetone, to give 1-(3,3diphenyl-3-cyanopropyl)-4-piperidino-4-piperidinecarboxamide, melting at about 149°C to 150°C.

Therapeutic Function

Analgesic

piritramide Preparation Products And Raw materials

Raw materials

Preparation Products

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piritramide Suppliers

302-41-0, piritramideRelated Search:


  • DipiritraMide
  • Pirdolan
  • piritramide
  • Pirtramide
  • Pirinitramide
  • A 65
  • Dipidolor
  • Piridolan
  • R 3365
  • 1-[3-cyano-3,3-di(phenyl)propyl]-4-piperidin-1-yl-piperidine-4-carboxamide
  • 1-[3-cyano-3,3-di(phenyl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide
  • 1-[3-cyano-3,3-di(phenyl)propyl]-4-piperidino-isonipecotamide
  • Piritramide (1.0mg/ml in Acetonitrile)
  • Piritramide (1 mg/mL in Methanol)
  • [1,4'-Bipiperidine]-4'-carboxamide, 1'-(3-cyano-3,3-diphenylpropyl)-
  • 302-41-0
  • C27H34N4O
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals