ChemicalBook > CAS DataBase List > 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride

Product Name
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
CAS No.
16899-81-3
Chemical Name
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
Synonyms
U 12844A;Isoprenaline impurity A;Norepinephrine Impurity 10;Isoprenaline EP Impurity A;Isoprenaline impurity A CRS;Isoprenaline EP Impurity A HCl;Isoprenaline HCl EP Impurity A;Isoprenaline HCl EP Impurity A HCl;Isoprenaline hydrochloride EP Impurity A;3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
CBNumber
CB4912824
Molecular Formula
C11H15NO3.ClH
Formula Weight
245.704
MOL File
16899-81-3.mol
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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Property

Melting point:
255-257℃
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001577
Product name
Isoprenaline impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001577
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
S346322
Product name
Isoprenaline impurity A
Purity
Aldrich
Packaging
50mg
Price
$179
Updated
2024/03/01
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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Chemical Properties,Usage,Production

Uses

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.

Preparation

Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%).

1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride Suppliers

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16899-81-3, 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochlorideRelated Search:

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  • 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride
  • Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1)
  • 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride
  • Isoprenaline impurity A
  • [2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE
  • U 12844A
  • 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE
  • Norepinephrine Impurity 10
  • Isoprenaline EP Impurity A HCl
  • Isoprenaline EP Impurity A
  • Isoprenaline impurity A CRS
  • Isoprenaline HCl EP Impurity A HCl
  • Isoprenaline hydrochloride EP Impurity A
  • Isoprenaline Hydrochloride Impurity 1（Isoprenaline Hydrochloride EP Impurity A）
  • 1-(3,4-dihydroxyphenyl)-2-(isopropyl amino) ethan-1-one Hydrochloride
  • 3，4-dihydroxyphenyl isopropylamino-methyl ketone hydrochloride
  • 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanone hydrochloride (Isoprenaline HCl Impurity)
  • 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethan-1-one, hydrochloride (1:1)
  • Isoprenaline HCl EP Impurity A
  • 16899-81-3