ChemicalBook > CAS DataBase List > levallorphan
levallorphan
- Product Name
- levallorphan
- CAS No.
- 152-02-3
- Chemical Name
- levallorphan
- Synonyms
- C07069;MCL 113;Naloxiphan;Levalorfano;levallorphan;Levallorphane;Levallorphanum;17-Allylmorphinan-3-ol;N-Allyl-3-hydroxymorphinan;l-N-Allyl-3-hydroxymorphinan
- CBNumber
- CB4928450
- Molecular Formula
- C19H25NO
- Formula Weight
- 283.41
- MOL File
- 152-02-3.mol
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levallorphan Property
- Melting point:
- 180-182°
- alpha
- D20 -88.9° (c = 3 in methanol)
- Boiling point:
- 425.96°C (rough estimate)
- Density
- 1.0260 (rough estimate)
- refractive index
- 1.5000 (estimate)
- pka
- 10.17±0.20(Predicted)
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Safety
- Hazardous Substances Data
- 152-02-3(Hazardous Substances Data)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0009181
- Product name
- LEVALLORPHAN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.28
- Updated
- 2021/12/16
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levallorphan Chemical Properties,Usage,Production
Definition
ChEBI: Levallorphan is a morphinane alkaloid.
brand name
Lorfan (Roche).
Clinical Use
Levallorphan is an opioid antagonist with practically no analgesic action. It has been used as one of the first relative pure antagonists for the treatment of opioid overdosage, to reverse opioid central depression and to antagonize opioidinduced respiratory impairment . The compound is now replaced by naloxone .
Synthesis
Starting material for the levallorphan
synthesis is 1-(4-methoxybenzyl)-
1,2,3,4,5,6,7,8-octahydro isoquinoline (1)
.
Purification Methods
It crystallises from aqueous EtOH. It is a narcotic antagonist. [Schneider & Grüssner Helv Chim Acta 34 2211 1951, Hellerbach Helv Chim Acta 39 429 1956.]
levallorphan Preparation Products And Raw materials
Raw materials
Preparation Products
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levallorphan Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74