ChemicalBook > CAS DataBase List > tert-butyl 4-hydroxybenzoate

tert-butyl 4-hydroxybenzoate

Uses

Product Name: tert-butyl 4-hydroxybenzoate
CAS No.: 25804-49-3
Chemical Name: tert-butyl 4-hydroxybenzoate
Synonyms: tert-Butyl p-hydroxybenzoate;tert-butyl 4-hydroxybenzoate;1,1-Dimethylethyl 4-hydroxybenzoate;p-Hydroxybenzoic acid tert-butyl ester;4-Hydroxy-benzoic acid tert-butyl ester;4-Hydroxybenzoic acid 1,1-dimethylethyl ester;Benzoic acid, 4-hydroxy-, 1,1-diMethylethyl ester
CBNumber: CB4935199
Molecular Formula: C11H14O3
Formula Weight: 194.23
MOL File: 25804-49-3.mol

Less

tert-butyl 4-hydroxybenzoate Property

Melting point:: 130-132 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
Boiling point:: 295.6±13.0 °C(Predicted)
Density: 1.107±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: 8.25±0.15(Predicted)
color: White

Less

Safety

HS Code: 2918290090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: T135775
Product name: tert-Butyl4-Hydroxybenzoate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0385389
Product name: TERT-BUTYL-4-HYDROXYBENZOATE
Purity: 95.00%
Packaging: 5MG
Price: $499.33
Updated: 2021/12/16

AK Scientific

Product number: J93192
Product name: tert-Butyl4-hydroxybenzoate
Packaging: 100g
Price: $525
Updated: 2021/12/16

Crysdot

Product number: CD12090919
Product name: tert-Butyl4-hydroxybenzoate
Purity: 97%
Packaging: 100g
Price: $539
Updated: 2021/12/16

Ambeed

Product number: A432876
Product name: tert-Butyl4-hydroxybenzoate
Purity: 96%
Packaging: 250mg
Price: $5
Updated: 2021/12/16

Less

tert-butyl 4-hydroxybenzoate Chemical Properties,Usage,Production

Uses

4-Hydroxybenzoate tert-butyl ester is used in organic synthesis, biochemical research, etc.

Synthesis

75-65-0

99-96-7

25804-49-3

Using p-hydroxybenzoic acid (1.50 g, 10.86 mmol) and tert-butanol (13.34 g, 18 mmol) as raw materials, DCC (2.5 g, 12.00 mmol) was dissolved in DCM (40 mL) catalyzed by DBU (0.19 mL, 1.20 mmol), and the reaction mixture was stirred vigorously for 18 hours at room temperature. After completion of the reaction, the solvent was evaporated to dryness and the residue was dissolved in DCM (50 mL) and filtered to remove insoluble material. The filtrate was washed sequentially with saturated NaHCO3 solution (50 mL), K2CO3 solution (2 x 50 mL) and saturated NaCl solution (50 mL). The organic phase was dried with MgSO4, filtered and the solvent was evaporated to give the crude product. The crude product was purified by column chromatography (EtOAc:hexane gradient elution) to afford tert-butyl 4-hydroxybenzoate (SO2-059) (31) as a white crystalline solid (1.1 g, 55% yield).1H NMR (400 MHz, CDCl3) δ 7.89 (d, J = 8.8 Hz, 1H), 6.84 (d, J = 8.9 Hz, 1H) 5.29 (s, 1H), 1.57 (s, 9H).

References

[1] Journal of Materials Chemistry, 2007, vol. 17, # 48, p. 5097 - 5110
[2] Synthesis, 2003, # 16, p. 2479 - 2482
[3] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 716 - 735
[4] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 14, p. 3645 - 3649
[5] Journal of Medicinal Chemistry, 2013, vol. 56, # 10, p. 3783 - 3805

tert-butyl 4-hydroxybenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

tert-butyl 4-hydroxybenzoate Suppliers

CHINA 72 India 1 Switzerland 1 United Kingdom 1 United States 2 Global 77

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9985
Advantage: 58

Win-Win Chemical CO., Limited

Tel: 0577-64498589 15325081899
Fax: 0577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 1083
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 5666
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shijiazhuang Leather Bureau Chemical Technology Co., Ltd.

Tel: 13020863400
Email: liaoy124@163.com
Country: China
ProdList: 293
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

Changzhou Ditong Chemical Co.,Ltd

Tel: +86-0519-88299272
Email: info@edengenechem.com
Country: China
ProdList: 2176
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Zhejiang Zetian Fine Chemical Co., Ltd

Tel: 0571-87682782 18957127338
Fax: QQ:3007632051
Email: sales@zetchem.com
Country: China
ProdList: 476
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Jinan Liheng Biotechnology Co., Ltd.

Tel: 15865262812
Email: info@lihengpharm.com
Country: CHINA
ProdList: 938
Advantage: 58

Richest Group Ltd

Tel: 18017061086
Email: oled@richest-group.com
Country: CHINA
ProdList: 5600
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18717800556
Email: sales@finebiotech.com
Country: China
ProdList: 2182
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Suzhou QIHANG Biotechnology Co., Ltd

Tel: 18662190603
Email: 437347250@qq.com
Country: China
ProdList: 4674
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8100
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Suzhou Xinrui Biotechnology Co., Ltd.

Tel: 13401437572
Email: xinruibiotech01@163.com
Country: China
ProdList: 2741
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Shanghai Yanbang Pharmaceutical Technology Co., Ltd

Tel: 15618536883
Email: 1228181347@qq.com
Country: China
ProdList: 7951
Advantage: 58

Heze Bona Medical Technology Co., LTD

Tel: 18615487702
Email: 614989876@qq.com
Country: China
ProdList: 3000
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-029-81123119 17391733320
Email: 1021@dideu.com
Country: China
ProdList: 10001
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 17715136450
Email: 2439673774@qq.com
Country: China
ProdList: 15647
Advantage: 58

Less

View Lastest Price from tert-butyl 4-hydroxybenzoate manufacturers

Career Henan Chemical Co

Product: tert-butyl 4-hydroxybenzoate 25804-49-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-09

25804-49-3, tert-butyl 4-hydroxybenzoateRelated Search:

1,1-DIMETHYL-2-PROPYNYL-4-METHOXYBENZOATE TERT-BUTYL 4-METHOXY-3-NITROBENZOATE 3'-HYDROXYMITORUBRIN TERT-BUTYL 4-(2-METHYL-4-NITROPHENOXY)BENZOATE 8-O-(4-METHOXYBENZOYL)-FORESTINE [2-(TERT-BUTOXYCARBONYL)-5-METHOXYPHENYL]BORONIC ACID tert-butyl 4-hydroxybenzoate TERT-BUTYL 4-(4-AMINO-2-METHYLPHENOXY)BENZOATE TERT-BUTYL 3,4,5-TRIMETHOXYBENZOATE ALTENUENE (-)-MITORUBRINIC ACID

tert-butyl 4-hydroxybenzoate

4-Hydroxybenzoic acid 1,1-dimethylethyl ester

Benzoic acid, 4-hydroxy-, 1,1-diMethylethyl ester

4-Hydroxy-benzoic acid tert-butyl ester

p-Hydroxybenzoic acid tert-butyl ester

tert-Butyl p-hydroxybenzoate

1,1-Dimethylethyl 4-hydroxybenzoate

25804-49-3